Asymmetric Organocatalysis of Activated Alkynes and Enynes

Akashdeep Sharma; Koppanathi Nagaraju; Gunda Ananda Rao; Ramani Gurubrahamam; Kwunmin Chen

doi:10.1002/ajoc.202100252

Asymmetric Organocatalysis of Activated Alkynes and Enynes

Akashdeep Sharma, Koppanathi Nagaraju, Gunda Ananda Rao, Ramani Gurubrahamam^*, Kwunmin Chen^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

13 Citations (Scopus)

Abstract

Enantioselective organocatalytic protocols for the functionalization of electron-deficient internal alkynes and enynes are reviewed. This review focuses on the applicability of activated conjugated π-systems in asymmetric synthesis for providing diversified chiral entities under metal-free reaction conditions. Various organocatalytic strategies with different catalytic modes are demonstrated.

Original language	English
Pages (from-to)	1567-1579
Number of pages	13
Journal	Asian Journal of Organic Chemistry
Volume	10
Issue number	7
DOIs	https://doi.org/10.1002/ajoc.202100252
Publication status	Published - 2021 Jul

Keywords

Alkynals
Alkynes
Alkynoates
Alkynones
Enantioselective
Enynes
Enynones
Organocatalysis

ASJC Scopus subject areas

Organic Chemistry

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10.1002/ajoc.202100252

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title = "Asymmetric Organocatalysis of Activated Alkynes and Enynes",

abstract = "Enantioselective organocatalytic protocols for the functionalization of electron-deficient internal alkynes and enynes are reviewed. This review focuses on the applicability of activated conjugated π-systems in asymmetric synthesis for providing diversified chiral entities under metal-free reaction conditions. Various organocatalytic strategies with different catalytic modes are demonstrated.",

keywords = "Alkynals, Alkynes, Alkynoates, Alkynones, Enantioselective, Enynes, Enynones, Organocatalysis",

author = "Akashdeep Sharma and Koppanathi Nagaraju and Rao, \{Gunda Ananda\} and Ramani Gurubrahamam and Kwunmin Chen",

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year = "2021",

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AU - Sharma, Akashdeep

AU - Nagaraju, Koppanathi

AU - Rao, Gunda Ananda

AU - Gurubrahamam, Ramani

AU - Chen, Kwunmin

PY - 2021/7

Y1 - 2021/7

N2 - Enantioselective organocatalytic protocols for the functionalization of electron-deficient internal alkynes and enynes are reviewed. This review focuses on the applicability of activated conjugated π-systems in asymmetric synthesis for providing diversified chiral entities under metal-free reaction conditions. Various organocatalytic strategies with different catalytic modes are demonstrated.

AB - Enantioselective organocatalytic protocols for the functionalization of electron-deficient internal alkynes and enynes are reviewed. This review focuses on the applicability of activated conjugated π-systems in asymmetric synthesis for providing diversified chiral entities under metal-free reaction conditions. Various organocatalytic strategies with different catalytic modes are demonstrated.

KW - Alkynals

KW - Alkynes

KW - Alkynoates

KW - Alkynones

KW - Enantioselective

KW - Enynes

KW - Enynones

KW - Organocatalysis

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UR - https://www.scopus.com/inward/citedby.url?scp=85107285079&partnerID=8YFLogxK

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DO - 10.1002/ajoc.202100252

M3 - Review article

AN - SCOPUS:85107285079

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VL - 10

SP - 1567

EP - 1579

JO - Asian Journal of Organic Chemistry

JF - Asian Journal of Organic Chemistry

IS - 7

ER -

Asymmetric Organocatalysis of Activated Alkynes and Enynes

Abstract

Keywords

ASJC Scopus subject areas

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