Asymmetric Organocatalysis of Activated Alkynes and Enynes

Akashdeep Sharma, Koppanathi Nagaraju, Gunda Ananda Rao, Ramani Gurubrahamam*, Kwunmin Chen*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)


Enantioselective organocatalytic protocols for the functionalization of electron-deficient internal alkynes and enynes are reviewed. This review focuses on the applicability of activated conjugated π-systems in asymmetric synthesis for providing diversified chiral entities under metal-free reaction conditions. Various organocatalytic strategies with different catalytic modes are demonstrated.

Original languageEnglish
Pages (from-to)1567-1579
Number of pages13
JournalAsian Journal of Organic Chemistry
Issue number7
Publication statusPublished - 2021 Jul


  • Alkynals
  • Alkynes
  • Alkynoates
  • Alkynones
  • Enantioselective
  • Enynes
  • Enynones
  • Organocatalysis

ASJC Scopus subject areas

  • Organic Chemistry


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