This paper substantiates the process of helping the clients with motor disabilities to operate computer. A team with multiple professionals from different disciplines served eight persons with quadriplegics diagnosed as Charcot-Marie-Tooth Disease, Amyotrophic Lateral Sclerosis (ALS), Athetoid Cerebral Palsy, Cervical Spinal Cord Injury and Muscular Dystrophy respectively. Based on the computer access approach (CAA), the limitations and strengths of motor control, the difficulties of operating computer and the context to support accessibility were evaluated. Furthermore, the evaluation results guided the configuration of computer system to be modified, possibly combined with changing anatomical control site. Finally better accessibility for each person was achieved. It can be concluded that CAA processed by an integrated team can greatly help in solving accessibility problems for quadriplegic.