Application of an OLED integrated with BEF and giant birefringent optical (GBO) film in a SPR biosensor

Briliant Adhi Prabowo, Ying Feng Chang, Yu Ying Lee, Li Chen Su, Chih Jen Yu, Yen Heng Lin, Chien Chou, Nan Fu Chiu, Hsin Chih Lai, Kou Chen Liu

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

This study aims to improve the signal sensitivity of a portable surface plasmon resonance (SPR) sensor system. An organic light emitting diode (OLED) was integrated with a brightness enhancement film (BEF) and a giant birefringent optical (GBO) film as a light source to construct the SPR based on an OLED-BEF-GBO film. A method for calculating the SPR signal by summing the differences in optical intensity at two different wavelengths was used to minimize the effect of the noise error that particularly occurs in a portable SPR device. The experimental results indicated that the limit of detection (LOD) of the SPR using an Au sensing layer has an effective refractive index change of 7.8 × 10-6 RIU. Furthermore, for the SPR using Au/Ag sensing metal layers, an LOD of 3.2 × 10-6 RIU was achieved due to the improved sensitivity and resolution value compared with the use of an Au sensing layer. The use of the SPR device in a bio-affinity assay to test the interaction between goat anti-mouse immunoglobulin G (IgG) and mouse IgG protein achieved a LOD of approximately 40.6 pg/mL.

Original languageEnglish
Pages (from-to)424-430
Number of pages7
JournalSensors and Actuators, B: Chemical
Volume198
DOIs
Publication statusPublished - 2014 Jul 31

Keywords

  • Biosensor
  • Brightness enhancement film (BEF)
  • GBO film
  • Organic light emitting diode (OLED)
  • Surface plasmon resonance (SPR)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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  • Cite this

    Prabowo, B. A., Chang, Y. F., Lee, Y. Y., Su, L. C., Yu, C. J., Lin, Y. H., Chou, C., Chiu, N. F., Lai, H. C., & Liu, K. C. (2014). Application of an OLED integrated with BEF and giant birefringent optical (GBO) film in a SPR biosensor. Sensors and Actuators, B: Chemical, 198, 424-430. https://doi.org/10.1016/j.snb.2014.03.041