Animal magnetocardiography using superconducting quantum interference device gradiometers assisted with magnetic nanoparticle injection: A sensitive method for early detecting electromagnetic changes induced by hypercholesterolemia

C. C. Wu, B. F. Hong, B. H. Wu, S. Y. Yang, H. E. Horng, H. C. Yang, W. Y.Isaac Tseng, W. K. Tseng, Y. B. Liu, L. C. Lin, L. S. Lu, Y. H. Lee

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Abstract

In this work, the authors used a superconducting quantum interference device (SQUID) magnetocardiography (MCG) system consisted of 64-channel low-transition-temperature SQUID gradiometers to detect the MCG signals of hepercholesterolemic rabbits. In addition, the MCG signals were recorded before and after the injection of magnetic nanoparticles into the rabbits' ear veins to investigate the effects of magnetic nanoparticles on the MCG signals. These MCG data were compared to those of normal rabbits to reveal the feasibility for early detection of the electromagnetic changes induced by hypercholesterolemia using MCG with the assistance of magnetic nanoparticle injection.

Original languageEnglish
Article number054111
JournalApplied Physics Letters
Volume90
Issue number5
DOIs
Publication statusPublished - 2007 Feb 19

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ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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