Abstract
Magnetic particle imaging (MPI) is a new medical imaging technology with a number of potential applications. It is based on utilizing the non-linear magnetization response for magnetic nanoparticles (MNPs). We have proposed a method to improve the detection sensitivity for the magnetization of MNPs, and their imaging technique, based on the detection of a second harmonic of the response using a high Tc SQUID. The advantage of using the second harmonic is that the response can be measured even with small amplitudes. In this paper, superparamagnetic MNPs with different diameters and different compositions of materials were analyzed by this method. In the MNPs, Resovist was found to be almost one order of magnitude larger than that of the other MNPs tested. The magnetic moments of the MNPs were estimated by fitting with the Langevin function to obtain the magnetic moments m of Resovist of 3.62×10−18 [J/T]. The magnetic moment m of Resovist was 7.4 times larger than the other MNPs.
| Original language | English |
|---|---|
| Pages (from-to) | 189-191 |
| Number of pages | 3 |
| Journal | Journal of Magnetism and Magnetic Materials |
| Volume | 440 |
| DOIs | |
| Publication status | Published - 2017 Oct 15 |
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Keywords
- Detection
- Harmonic
- Magnetic sensor
- Nanoparticle
- SQUID
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
Cite this
Analysis of magnetic nanoparticles using second harmonic responses. / Tanaka, Saburo; Suzuki, Toshifumi; Kobayashi, Kazuya; Liao, Shu-Hsien; Horng, Herng-Er; Yang, Hong Chang.
In: Journal of Magnetism and Magnetic Materials, Vol. 440, 15.10.2017, p. 189-191.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Analysis of magnetic nanoparticles using second harmonic responses
AU - Tanaka, Saburo
AU - Suzuki, Toshifumi
AU - Kobayashi, Kazuya
AU - Liao, Shu-Hsien
AU - Horng, Herng-Er
AU - Yang, Hong Chang
PY - 2017/10/15
Y1 - 2017/10/15
N2 - Magnetic particle imaging (MPI) is a new medical imaging technology with a number of potential applications. It is based on utilizing the non-linear magnetization response for magnetic nanoparticles (MNPs). We have proposed a method to improve the detection sensitivity for the magnetization of MNPs, and their imaging technique, based on the detection of a second harmonic of the response using a high Tc SQUID. The advantage of using the second harmonic is that the response can be measured even with small amplitudes. In this paper, superparamagnetic MNPs with different diameters and different compositions of materials were analyzed by this method. In the MNPs, Resovist was found to be almost one order of magnitude larger than that of the other MNPs tested. The magnetic moments of the MNPs were estimated by fitting with the Langevin function to obtain the magnetic moments m of Resovist of 3.62×10−18 [J/T]. The magnetic moment m of Resovist was 7.4 times larger than the other MNPs.
AB - Magnetic particle imaging (MPI) is a new medical imaging technology with a number of potential applications. It is based on utilizing the non-linear magnetization response for magnetic nanoparticles (MNPs). We have proposed a method to improve the detection sensitivity for the magnetization of MNPs, and their imaging technique, based on the detection of a second harmonic of the response using a high Tc SQUID. The advantage of using the second harmonic is that the response can be measured even with small amplitudes. In this paper, superparamagnetic MNPs with different diameters and different compositions of materials were analyzed by this method. In the MNPs, Resovist was found to be almost one order of magnitude larger than that of the other MNPs tested. The magnetic moments of the MNPs were estimated by fitting with the Langevin function to obtain the magnetic moments m of Resovist of 3.62×10−18 [J/T]. The magnetic moment m of Resovist was 7.4 times larger than the other MNPs.
KW - Detection
KW - Harmonic
KW - Magnetic sensor
KW - Nanoparticle
KW - SQUID
UR - http://www.scopus.com/inward/record.url?scp=85008467908&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85008467908&partnerID=8YFLogxK
U2 - 10.1016/j.jmmm.2016.12.067
DO - 10.1016/j.jmmm.2016.12.067
M3 - Article
AN - SCOPUS:85008467908
VL - 440
SP - 189
EP - 191
JO - Journal of Magnetism and Magnetic Materials
JF - Journal of Magnetism and Magnetic Materials
SN - 0304-8853
ER -