Analysis of magnetic nanoparticles using second harmonic responses

Saburo Tanaka, Toshifumi Suzuki, Kazuya Kobayashi, Shu-Hsien Liao, Herng-Er Horng, Hong Chang Yang

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    Magnetic particle imaging (MPI) is a new medical imaging technology with a number of potential applications. It is based on utilizing the non-linear magnetization response for magnetic nanoparticles (MNPs). We have proposed a method to improve the detection sensitivity for the magnetization of MNPs, and their imaging technique, based on the detection of a second harmonic of the response using a high Tc SQUID. The advantage of using the second harmonic is that the response can be measured even with small amplitudes. In this paper, superparamagnetic MNPs with different diameters and different compositions of materials were analyzed by this method. In the MNPs, Resovist was found to be almost one order of magnitude larger than that of the other MNPs tested. The magnetic moments of the MNPs were estimated by fitting with the Langevin function to obtain the magnetic moments m of Resovist of 3.62×10−18 [J/T]. The magnetic moment m of Resovist was 7.4 times larger than the other MNPs.

    Original languageEnglish
    Pages (from-to)189-191
    Number of pages3
    JournalJournal of Magnetism and Magnetic Materials
    Volume440
    DOIs
    Publication statusPublished - 2017 Oct 15

    Fingerprint

    Nanoparticles
    harmonics
    nanoparticles
    Magnetic moments
    magnetic moments
    Magnetization
    Imaging techniques
    magnetization
    SQUIDs
    Medical imaging
    imaging techniques
    Chemical analysis
    ferumoxides

    Keywords

    • Detection
    • Harmonic
    • Magnetic sensor
    • Nanoparticle
    • SQUID

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics

    Cite this

    Analysis of magnetic nanoparticles using second harmonic responses. / Tanaka, Saburo; Suzuki, Toshifumi; Kobayashi, Kazuya; Liao, Shu-Hsien; Horng, Herng-Er; Yang, Hong Chang.

    In: Journal of Magnetism and Magnetic Materials, Vol. 440, 15.10.2017, p. 189-191.

    Research output: Contribution to journalArticle

    Tanaka, Saburo ; Suzuki, Toshifumi ; Kobayashi, Kazuya ; Liao, Shu-Hsien ; Horng, Herng-Er ; Yang, Hong Chang. / Analysis of magnetic nanoparticles using second harmonic responses. In: Journal of Magnetism and Magnetic Materials. 2017 ; Vol. 440. pp. 189-191.
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    AU - Suzuki, Toshifumi

    AU - Kobayashi, Kazuya

    AU - Liao, Shu-Hsien

    AU - Horng, Herng-Er

    AU - Yang, Hong Chang

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