@inproceedings{aefb242ae083420d9c14fe3597ea58d9,
title = "An implantable multifunctional needle type biosensor with integrated RF capability",
abstract = "We report the development of an implantable multifunctional (glucose and cholesterol) needle type biosensor with integrated RF wireless circuitry for continuous in vivo monitoring of metabolites during short term stays in emergency room or intensive care unit. Silicon-based MEMS technologies are used for the fabrication of micro needle sensors. The whole device is covered by a biocompatible Parylene layer with opening structure at the active areas of electrodes. Electropolymerization of active biomolecules and conducting polymer provides in situ nanoscale physical entrapments of various oxidoreductases (Glucose oxidase and cholesterol oxidase) and functions as a viable matrix for the construction of micro amperometric biosensors. Hybrid CMOS fabrication processes are used to accomplish the 433 MHz ASK RF transmitter and receiver (0.18μm CMOS 1P6M process) and the data converter (0.35μm CMOS 2P4M process). We will present and discuss the detail design and the integrated system performance in this paper.",
keywords = "Biosensors, Cholesterol, Glucose, Implantable, Multifunction, Needle type, Parylene, Polypyrrole, Wireless",
author = "Chiu, {Nan Fu} and Wang, {Jmin Min} and Liao, {Cheng Wei} and Chen, {Chun Hao} and Chen, {Hsiao Chin} and Yang, {Lung Jieh} and Lu, {Shey Shi} and Lin, {Chii Wann}",
year = "2005",
language = "English",
isbn = "0780387406",
series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
pages = "1933--1936",
booktitle = "Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005",
note = "2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 ; Conference date: 01-09-2005 Through 04-09-2005",
}