Abstract
A highly enantioselective cascade reaction for the generation of five quaternary stereocenters in one-pot operation is reported for the first time in the history of organic synthesis. Cinchona-alkaloid derived hydrogen-bonding catalyst furnished structurally complex cascade products from simple substrates in excellent yields and stereoselectivities.
| Original language | English |
|---|---|
| Pages (from-to) | 7649-7652 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 53 |
| Issue number | 54 |
| DOIs | |
| Publication status | Published - 2017 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
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Dive into the research topics of 'An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones'. Together they form a unique fingerprint.Datasets
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CCDC 1526049: Experimental Crystal Structure Determination
Yang, S.-M. (Creator), Reddy, G. M. (Creator), Wang, T.-P. (Creator), Yeh, Y.-S. (Creator), Wang, M. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1n6zd7, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1n6zd7&sid=DataCite
Dataset
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CCDC 1473859: Experimental Crystal Structure Determination
Yang, S.-M. (Creator), Reddy, G. M. (Creator), Wang, T.-P. (Creator), Yeh, Y.-S. (Creator), Wang, M. (Creator) & Lin, W. (Creator), Unknown Publisher, 2017
DOI: 10.5517/ccdc.csd.cc1lgnvk, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1lgnvk&sid=DataCite
Dataset