An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones

Shu Mei Yang, Ganapuram Madhusudhan Reddy, Tzu Ping Wang, Yu Sheng Yeh, Min Wang, Wenwei Lin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A highly enantioselective cascade reaction for the generation of five quaternary stereocenters in one-pot operation is reported for the first time in the history of organic synthesis. Cinchona-alkaloid derived hydrogen-bonding catalyst furnished structurally complex cascade products from simple substrates in excellent yields and stereoselectivities.

Original languageEnglish
Pages (from-to)7649-7652
Number of pages4
JournalChemical Communications
Volume53
Issue number54
DOIs
Publication statusPublished - 2017 Jan 1

Fingerprint

Cinchona Alkaloids
Synthetic Chemistry Techniques
Stereoselectivity
Hydrogen Bonding
Hydrogen bonds
History
Catalysts
Substrates

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones. / Yang, Shu Mei; Reddy, Ganapuram Madhusudhan; Wang, Tzu Ping; Yeh, Yu Sheng; Wang, Min; Lin, Wenwei.

In: Chemical Communications, Vol. 53, No. 54, 01.01.2017, p. 7649-7652.

Research output: Contribution to journalArticle

Yang, Shu Mei ; Reddy, Ganapuram Madhusudhan ; Wang, Tzu Ping ; Yeh, Yu Sheng ; Wang, Min ; Lin, Wenwei. / An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones. In: Chemical Communications. 2017 ; Vol. 53, No. 54. pp. 7649-7652.
@article{deae393770e84c8d931462d5ad01c10b,
title = "An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones",
abstract = "A highly enantioselective cascade reaction for the generation of five quaternary stereocenters in one-pot operation is reported for the first time in the history of organic synthesis. Cinchona-alkaloid derived hydrogen-bonding catalyst furnished structurally complex cascade products from simple substrates in excellent yields and stereoselectivities.",
author = "Yang, {Shu Mei} and Reddy, {Ganapuram Madhusudhan} and Wang, {Tzu Ping} and Yeh, {Yu Sheng} and Min Wang and Wenwei Lin",
year = "2017",
month = "1",
day = "1",
doi = "10.1039/c7cc03995f",
language = "English",
volume = "53",
pages = "7649--7652",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "54",

}

TY - JOUR

T1 - An enantioselective cascade for simultaneous generation of five quaternary stereocenters from fully substituted enones

AU - Yang, Shu Mei

AU - Reddy, Ganapuram Madhusudhan

AU - Wang, Tzu Ping

AU - Yeh, Yu Sheng

AU - Wang, Min

AU - Lin, Wenwei

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A highly enantioselective cascade reaction for the generation of five quaternary stereocenters in one-pot operation is reported for the first time in the history of organic synthesis. Cinchona-alkaloid derived hydrogen-bonding catalyst furnished structurally complex cascade products from simple substrates in excellent yields and stereoselectivities.

AB - A highly enantioselective cascade reaction for the generation of five quaternary stereocenters in one-pot operation is reported for the first time in the history of organic synthesis. Cinchona-alkaloid derived hydrogen-bonding catalyst furnished structurally complex cascade products from simple substrates in excellent yields and stereoselectivities.

UR - http://www.scopus.com/inward/record.url?scp=85022029865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85022029865&partnerID=8YFLogxK

U2 - 10.1039/c7cc03995f

DO - 10.1039/c7cc03995f

M3 - Article

AN - SCOPUS:85022029865

VL - 53

SP - 7649

EP - 7652

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 54

ER -