An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions

Yi Ling Tsai; Yu Shiou Fan; Chia Jui Lee; Chan Hui Huang; Utpal Das; Wenwei Lin

doi:10.1039/c3cc45862h

An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions

Yi Ling Tsai
, Yu Shiou Fan
, Chia Jui Lee
, Chan Hui Huang
, Utpal Das
, Wenwei Lin^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.

Original language	English
Pages (from-to)	10308-10310
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	87
DOIs	https://doi.org/10.1039/c3cc45862h
Publication status	Published - 2013 Oct 8

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c3cc45862h

Cite this

@article{050fa91a366d410e9776fe6d5e960f28,

title = "An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions",

abstract = "Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.",

author = "Tsai, \{Yi Ling\} and Fan, \{Yu Shiou\} and Lee, \{Chia Jui\} and Huang, \{Chan Hui\} and Utpal Das and Wenwei Lin",

year = "2013",

month = oct,

day = "8",

doi = "10.1039/c3cc45862h",

language = "English",

volume = "49",

pages = "10308--10310",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "87",

}

TY - JOUR

T1 - An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions

AU - Tsai, Yi Ling

AU - Fan, Yu Shiou

AU - Lee, Chia Jui

AU - Huang, Chan Hui

AU - Das, Utpal

AU - Lin, Wenwei

PY - 2013/10/8

Y1 - 2013/10/8

N2 - Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.

AB - Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.

UR - https://www.scopus.com/pages/publications/85033243791

UR - https://www.scopus.com/pages/publications/85033243791#tab=citedBy

U2 - 10.1039/c3cc45862h

DO - 10.1039/c3cc45862h

M3 - Article

AN - SCOPUS:85033243791

SN - 1359-7345

VL - 49

SP - 10308

EP - 10310

JO - Chemical Communications

JF - Chemical Communications

IS - 87

ER -

An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this