An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions

Yi Ling Tsai, Yu Shiou Fan, Chia Jui Lee, Chan Hui Huang, Utpal Das, Wenwei Lin

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.

Original languageEnglish
Pages (from-to)10308-10310
Number of pages3
JournalChemical Communications
Volume49
Issue number87
DOIs
Publication statusPublished - 2013 Oct 8

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Oxazoles
Acylation
Phosphorus
Esters

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions. / Tsai, Yi Ling; Fan, Yu Shiou; Lee, Chia Jui; Huang, Chan Hui; Das, Utpal; Lin, Wenwei.

In: Chemical Communications, Vol. 49, No. 87, 08.10.2013, p. 10308-10310.

Research output: Contribution to journalArticle

Tsai, Yi Ling ; Fan, Yu Shiou ; Lee, Chia Jui ; Huang, Chan Hui ; Das, Utpal ; Lin, Wenwei. / An efficient synthesis of trisubstituted oxazoles via chemoselective o-acylations and intramolecular wittig reactions. In: Chemical Communications. 2013 ; Vol. 49, No. 87. pp. 10308-10310.
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