An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes

Chun Wei Kuo, Chun Chao Wang, Hu Lin Fang, B. Rama Raju, Veerababurao Kavala, Pateliya Mujjamil Habib, Ching Fa Yao

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

An efficient and practical method for the synthesis of indolyl-nitroalkane derivatives catalyzed by N-bromosuccinimide is described. The generality of this method was demonstrated by synthesizing an array of diverse 3-substituted indole derivatives by the reaction of different β-nitrostyrenes with various substituted indoles. Simple reaction conditions accompanied by good yields of indolyl-nitroalkanes are the merits of this methodology.

Original languageEnglish
Pages (from-to)3952-3963
Number of pages12
JournalMolecules
Volume14
Issue number10
DOIs
Publication statusPublished - 2009 Oct 1

Fingerprint

Bromosuccinimide
Derivatives
Indoles
indole

Keywords

  • Friedel-Crafts alkylation
  • Indolyl-nitroalkane
  • N-bromosuccinimide
  • Nitroalkenes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Kuo, C. W., Wang, C. C., Fang, H. L., Raju, B. R., Kavala, V., Habib, P. M., & Yao, C. F. (2009). An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes. Molecules, 14(10), 3952-3963. https://doi.org/10.3390/molecules14103952

An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes. / Kuo, Chun Wei; Wang, Chun Chao; Fang, Hu Lin; Raju, B. Rama; Kavala, Veerababurao; Habib, Pateliya Mujjamil; Yao, Ching Fa.

In: Molecules, Vol. 14, No. 10, 01.10.2009, p. 3952-3963.

Research output: Contribution to journalArticle

Kuo, CW, Wang, CC, Fang, HL, Raju, BR, Kavala, V, Habib, PM & Yao, CF 2009, 'An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes', Molecules, vol. 14, no. 10, pp. 3952-3963. https://doi.org/10.3390/molecules14103952
Kuo CW, Wang CC, Fang HL, Raju BR, Kavala V, Habib PM et al. An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes. Molecules. 2009 Oct 1;14(10):3952-3963. https://doi.org/10.3390/molecules14103952
Kuo, Chun Wei ; Wang, Chun Chao ; Fang, Hu Lin ; Raju, B. Rama ; Kavala, Veerababurao ; Habib, Pateliya Mujjamil ; Yao, Ching Fa. / An efficient method for the N-bromosuccinimide catalyzed synthesis of indolyl-nitroalkanes. In: Molecules. 2009 ; Vol. 14, No. 10. pp. 3952-3963.
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