An easy and efficient synthesis of 3-nitrochromans

Ching Fa Yao, Yeong Jiunn Jang, Ming Chung Yan

Research output: Contribution to journalArticle

32 Citations (Scopus)


The reaction of nitro olefins reacted with (E)-(2-hydroxyphenyl)-1-nitroethylene in the presence of DABCO generates 3-nitrochroman with a high stereoselectivity. A possible reaction mechanism for the reaction and the transition states involved in producing the final product are proposed. The treatment of 3-nitrochromans with t-BuOK give alkenes.

Original languageEnglish
Pages (from-to)3813-3816
Number of pages4
JournalTetrahedron Letters
Issue number19
Publication statusPublished - 2003 May 5


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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