An easy access to carbazolones and 2,3-disubstituted indoles

Donala Janreddy, Veerababurao Kavala, J. W.John Bosco, Chun Wei Kuo, Ching Fa Yao

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.

Original languageEnglish
Pages (from-to)2360-2365
Number of pages6
JournalEuropean Journal of Organic Chemistry
Issue number12
DOIs
Publication statusPublished - 2011 Apr 1

Keywords

  • Cyclization
  • Iron
  • Nitrogen heterocycles

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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