Abstract
Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.
| Original language | English |
|---|---|
| Pages (from-to) | 2360-2365 |
| Number of pages | 6 |
| Journal | European Journal of Organic Chemistry |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2011 Apr 1 |
Keywords
- Cyclization
- Iron
- Nitrogen heterocycles
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
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Janreddy, D., Kavala, V., Bosco, J. W. J., Kuo, C. W., & Yao, C. F. (2011). An easy access to carbazolones and 2,3-disubstituted indoles. European Journal of Organic Chemistry, (12), 2360-2365. https://doi.org/10.1002/ejoc.201001357