Abstract
Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.
| Original language | English |
|---|---|
| Pages (from-to) | 2360-2365 |
| Number of pages | 6 |
| Journal | European Journal of Organic Chemistry |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2011 Apr 1 |
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Keywords
- Cyclization
- Iron
- Nitrogen heterocycles
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
An easy access to carbazolones and 2,3-disubstituted indoles. / Janreddy, Donala; Kavala, Veerababurao; Bosco, J. W.John; Kuo, Chun Wei; Yao, Ching Fa.
In: European Journal of Organic Chemistry, No. 12, 01.04.2011, p. 2360-2365.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An easy access to carbazolones and 2,3-disubstituted indoles
AU - Janreddy, Donala
AU - Kavala, Veerababurao
AU - Bosco, J. W.John
AU - Kuo, Chun Wei
AU - Yao, Ching Fa
PY - 2011/4/1
Y1 - 2011/4/1
N2 - Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.
AB - Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.
KW - Cyclization
KW - Iron
KW - Nitrogen heterocycles
UR - http://www.scopus.com/inward/record.url?scp=79953711492&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953711492&partnerID=8YFLogxK
U2 - 10.1002/ejoc.201001357
DO - 10.1002/ejoc.201001357
M3 - Article
AN - SCOPUS:79953711492
SP - 2360
EP - 2365
JO - Annalen der Pharmacie
JF - Annalen der Pharmacie
SN - 0075-4617
IS - 12
ER -