TY - JOUR
T1 - An easy access to carbazolones and 2,3-disubstituted indoles
AU - Janreddy, Donala
AU - Kavala, Veerababurao
AU - Bosco, J. W.John
AU - Kuo, Chun Wei
AU - Yao, Ching Fa
PY - 2011/4/1
Y1 - 2011/4/1
N2 - Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.
AB - Synthesis of carbazol-4-ones, 3,4-dihydrocyclopental-indol-1-one, and indole derivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation of 3-hydroxy-2-(2-nitrophenyl)enones is demonstrated. The same protocol has been extended to access indolocarbazolone and indoloquinolone derivatives. Synthesis ofderivatives by a Fe/AcOH-mediated intramolecular reductive N-heteroannulation strategy is demonstrated. The starting materials were easily accessed from C-arylation of 1,3-diketones by o-nitroiodobenzenes.
KW - Cyclization
KW - Iron
KW - Nitrogen heterocycles
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U2 - 10.1002/ejoc.201001357
DO - 10.1002/ejoc.201001357
M3 - Article
AN - SCOPUS:79953711492
SP - 2360
EP - 2365
JO - Justus Liebigs Annalen der Chemie
JF - Justus Liebigs Annalen der Chemie
SN - 0075-4617
IS - 12
ER -