Advanced plasmonic biosensing devices and automation systems for disease diagnostic and drug screening applications

Nan-Fu Chiu, Tzuu Shaang Wey, Chun Yu, Tzu Chien Hsiao, Chii Wann Lin

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    4 Citations (Scopus)

    Abstract

    Bio-plasmonics is proposed for the research and development of novel devices, which use biomolecules as a part of the plasmon oscillation system to actively interact with nano/micro structure. We have reported a novel design of Surface Plasmon Resonance (SPR) device and system, which uses alternative dielectric layers to enhance the SPR signal quality and modulate its resonant position. The use of biomolecular thin film, such as DNAs or Proteins, in this design can result in resonant condition of wavelength changes and thus can be detected by using nano-grating in the scattering mode with ehanced feature due to resonance. According to our calculation, it can provide ultra sensitivity system (dLx/dn) of 10 8 for biosensor applications. The fundamental SPR principle and extended application of these fundamental principles and novel devices, including screening and diagnosis, will be discussed SPR-system to control is the ability. SPR-system has the ability to detect, in near real-time, the concentration of a target analyte and biosensing is viewed as a key application domain for this new technology.

    Original languageEnglish
    Title of host publicationProceedings - 8th International Conference on Intelligent Systems Design and Applications, ISDA 2008
    Pages171-176
    Number of pages6
    DOIs
    Publication statusPublished - 2008 Dec 1
    Event8th International Conference on Intelligent Systems Design and Applications, ISDA 2008 - Kaohsiung, Taiwan
    Duration: 2008 Nov 262008 Nov 28

    Publication series

    NameProceedings - 8th International Conference on Intelligent Systems Design and Applications, ISDA 2008
    Volume1

    Other

    Other8th International Conference on Intelligent Systems Design and Applications, ISDA 2008
    CountryTaiwan
    CityKaohsiung
    Period08/11/2608/11/28

    Keywords

    • Bio-plasmonics
    • Biosensor
    • DNAs
    • Proteins
    • Surface plasmon polaritons (SPPs)

    ASJC Scopus subject areas

    • Artificial Intelligence
    • Control and Systems Engineering

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