The popular online social networks are increasingly used by business organizations for various business activities. This research focused on the adoption of online social networks by human resources (HR) professionals as a tool in organizational staffing activities. The Technology Acceptance Model (TAM) was the theoretical basis of this study which sought to investigate the issue with a multi-country sample. Online questionnaire invitations were sent to HR practitioners in Taiwan, India, Spain and Guatemala, which generated 101 valid responses. Partial least square-based structural equation modeling was used to fit the proposed model and test the research hypotheses. Results indicated that, as hypothesized, the perceived usefulness, perceived ease of use, and subjective norms in TAM model effectively explained HR practitioners’ behavioral intention to use online social networks for staffing activities in our sample. Limitations and future research were also discussed.