Abstract
An efficient and attractive synthesis of a series of novel poly-functionalized phosphorus zwitterions was achieved via three-component reactions of the corresponding functional nucleophiles, aldehydes, and Bu 3P in the presence of acidic promoter. These polysubstituted zwitterions could regioselectively undergo further transformations to synthetically important furanonaphthoquinones and related products via the intramolecular Wittig reaction. These methods could have potential application in synthetic and pharmaceutical chemistry for its facilitation and easily accessible commercial materials.
| Original language | English |
|---|---|
| Pages (from-to) | 828-834 |
| Number of pages | 7 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 11 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2013 Feb 7 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Wu, Z. Z., Jang, Y. J., Lee, C. J., Lee, Y. T., & Lin, W. (2013). A versatile and practical method for regioselective synthesis of polysubstituted furanonaphthoquinones. Organic and Biomolecular Chemistry, 11(5), 828-834. https://doi.org/10.1039/c2ob26986d