Abstract
An efficient and attractive synthesis of a series of novel poly-functionalized phosphorus zwitterions was achieved via three-component reactions of the corresponding functional nucleophiles, aldehydes, and Bu 3P in the presence of acidic promoter. These polysubstituted zwitterions could regioselectively undergo further transformations to synthetically important furanonaphthoquinones and related products via the intramolecular Wittig reaction. These methods could have potential application in synthetic and pharmaceutical chemistry for its facilitation and easily accessible commercial materials.
| Original language | English |
|---|---|
| Pages (from-to) | 828-834 |
| Number of pages | 7 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 11 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2013 Feb 7 |
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ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
A versatile and practical method for regioselective synthesis of polysubstituted furanonaphthoquinones. / Wu, Zong Ze; Jang, Yeong Jiunn; Lee, Chia Jui; Lee, Yen Te; Lin, Wenwei.
In: Organic and Biomolecular Chemistry, Vol. 11, No. 5, 07.02.2013, p. 828-834.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A versatile and practical method for regioselective synthesis of polysubstituted furanonaphthoquinones
AU - Wu, Zong Ze
AU - Jang, Yeong Jiunn
AU - Lee, Chia Jui
AU - Lee, Yen Te
AU - Lin, Wenwei
PY - 2013/2/7
Y1 - 2013/2/7
N2 - An efficient and attractive synthesis of a series of novel poly-functionalized phosphorus zwitterions was achieved via three-component reactions of the corresponding functional nucleophiles, aldehydes, and Bu 3P in the presence of acidic promoter. These polysubstituted zwitterions could regioselectively undergo further transformations to synthetically important furanonaphthoquinones and related products via the intramolecular Wittig reaction. These methods could have potential application in synthetic and pharmaceutical chemistry for its facilitation and easily accessible commercial materials.
AB - An efficient and attractive synthesis of a series of novel poly-functionalized phosphorus zwitterions was achieved via three-component reactions of the corresponding functional nucleophiles, aldehydes, and Bu 3P in the presence of acidic promoter. These polysubstituted zwitterions could regioselectively undergo further transformations to synthetically important furanonaphthoquinones and related products via the intramolecular Wittig reaction. These methods could have potential application in synthetic and pharmaceutical chemistry for its facilitation and easily accessible commercial materials.
UR - http://www.scopus.com/inward/record.url?scp=84872093610&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872093610&partnerID=8YFLogxK
U2 - 10.1039/c2ob26986d
DO - 10.1039/c2ob26986d
M3 - Article
C2 - 23235915
AN - SCOPUS:84872093610
VL - 11
SP - 828
EP - 834
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 5
ER -