A sperm testing device on a liquid crystal and polymer composite film

Yi Hsin Lin, Ting Yu Chu, Wei Lin Chu, Yu Shih Tsou, Ya Ping Chiu, Farn Lu, Wan Chen Tsai, Shin Tson Wu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Developing a handy sperm testing device is important since sperm quality is a significant factor for fertility potential. In this paper, we demonstrate a sperm testing device based on a switchable surface, a liquid crystal and polymer composite film (LCPCF). The wettability of LCPCF is electrically switchable due to the electrically tunable orientations of liquid crystal molecules. In experiments, two motions of a semen drop on switchable surface of LCPCF are observed: back-and-forth stretches and collapses of semen drops. The better quality spermatozoa results in back-and-forth stretches of a semen drop on LCPCF; otherwise, the semen drop collapses. The motility and concentration of semen can also be sensed by the stretch distance and collapse distance of semen drops, respectively. The mechanism of back-and-forth stretches of semen drops results from fertile sperms swimming against the flow with the periodic changes of the orientation of LC molecules with pulsed voltages. The mechanism of collapses of semen drops results from the washed-away infertile sperms which are deposited on LCPCF and then re-modify surface of LCPCF. Potential applications for this device include sperm testers and microfluidic devices for Assisted Reproductive Technology.

Original languageEnglish
Article numberS9
JournalJournal of Nanomedicine and Nanotechnology
Volume4
Issue number4
DOIs
Publication statusPublished - 2013 Oct 4

Fingerprint

Composite films
Semen
Polymer films
Liquid crystals
Spermatozoa
Equipment and Supplies
Testing
Lab-On-A-Chip Devices
Liquid Crystals
Molecules
Wettability
Microfluidics
Assisted Reproductive Techniques
Wetting
liquid crystal polymer
Crystal orientation
Fertility
Electric potential
Experiments

Keywords

  • LC
  • Liquid crystal
  • Sperm testing
  • Switchable surface

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering
  • Medicine (miscellaneous)
  • Pharmaceutical Science

Cite this

A sperm testing device on a liquid crystal and polymer composite film. / Lin, Yi Hsin; Chu, Ting Yu; Chu, Wei Lin; Tsou, Yu Shih; Chiu, Ya Ping; Lu, Farn; Tsai, Wan Chen; Wu, Shin Tson.

In: Journal of Nanomedicine and Nanotechnology, Vol. 4, No. 4, S9, 04.10.2013.

Research output: Contribution to journalArticle

Lin, Yi Hsin ; Chu, Ting Yu ; Chu, Wei Lin ; Tsou, Yu Shih ; Chiu, Ya Ping ; Lu, Farn ; Tsai, Wan Chen ; Wu, Shin Tson. / A sperm testing device on a liquid crystal and polymer composite film. In: Journal of Nanomedicine and Nanotechnology. 2013 ; Vol. 4, No. 4.
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