Abstract
A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.
Original language | English |
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Pages (from-to) | 1187-1192 |
Number of pages | 6 |
Journal | Tetrahedron |
Volume | 67 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2011 Feb 11 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry