A selective glucose sensor: The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers

Ching Hua Tsai, Yi Hsuan Tang, Hui Ting Chen, Yi Wen Yao, Tun Cheng Chien, Chai Lin Kao

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Selective glucose binding was identified through five generations of monoboronic acid-functionalized PAMAM dendrimers. The best selectivity obtained when using G3 dendrimers (1b) generated 71.1, 94.9, and 1309 times stronger binding than when using galactose, fructose, and lactose, respectively. Further experiments using dendrimer analogues and glucose derivatives suggested that two nearby monoboronic acids cooperatively bound one glucose.

Original languageEnglish
Pages (from-to)4577-4580
Number of pages4
JournalChemical Communications
Volume54
Issue number36
DOIs
Publication statusPublished - 2018 Jan 1

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Glucose sensors
Dendrimers
Glucose
Acids
Fructose
Lactose
Galactose
Derivatives
Poly(amidoamine)
Experiments

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

A selective glucose sensor : The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers. / Tsai, Ching Hua; Tang, Yi Hsuan; Chen, Hui Ting; Yao, Yi Wen; Chien, Tun Cheng; Kao, Chai Lin.

In: Chemical Communications, Vol. 54, No. 36, 01.01.2018, p. 4577-4580.

Research output: Contribution to journalArticle

Tsai, Ching Hua ; Tang, Yi Hsuan ; Chen, Hui Ting ; Yao, Yi Wen ; Chien, Tun Cheng ; Kao, Chai Lin. / A selective glucose sensor : The cooperative effect of monoboronic acid-modified poly(amidoamine) dendrimers. In: Chemical Communications. 2018 ; Vol. 54, No. 36. pp. 4577-4580.
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