A novel hybrid metal-organic framework-polymeric monolith for solid-phase microextraction

Chen Lan Lin, Stephen Lirio, Ya Ting Chen, Chia Her Lin*, Hsi Ya Huang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

59 Citations (Scopus)

Abstract

This study describes the fabrication of a novel hybrid metal-organic framework- organic polymer (MOF-polymer) for use as a stationary phase in fritless solid-phase microextraction (SPME) for validating analytical methods. The MOF-polymer was prepared by using ethylene dimethacrylate (EDMA), butyl methacrylate (BMA), and an imidazolium-based ionic liquid as porogenic solvent followed by microwave-assisted polymerization with the addition of 25 % MOF. This novel hybrid MOF-polymer was used to extract penicillin (penicillin G, penicillin V, oxacillin, cloxacillin, nafcillin, dicloxacillin) under different conditions. Quantitative analysis of the extracted penicillin samples using the MOF-organic polymer for SPME was conducted by using capillary electrochromatography (CEC) coupled with UV analysis. The penicillin recovery was 63-96.2 % with high reproducibility, sensitivity, and reusability. The extraction time with the proposed fabricated SPME was only 34 min.

Original languageEnglish
Pages (from-to)3317-3321
Number of pages5
JournalChemistry - A European Journal
Volume20
Issue number12
DOIs
Publication statusPublished - 2014 Mar 17
Externally publishedYes

Keywords

  • capillary electrochromatography
  • metal-organic frameworks
  • penicillin
  • polymers
  • solid-phase microextraction

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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