A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Deepak Kumar Barange; B. Rama Raju; Veerababurao Kavala; Chun Wei Kuo; Yu Chen Tu; Ching Fa Yao

doi:10.1016/j.tet.2010.03.051

A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Deepak Kumar Barange, B. Rama Raju, Veerababurao Kavala, Chun Wei Kuo, Yu Chen Tu, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.

Original language	English
Pages (from-to)	3754-3760
Number of pages	7
Journal	Tetrahedron
Volume	66
Issue number	21
DOIs	https://doi.org/10.1016/j.tet.2010.03.051
Publication status	Published - 2010 May 22

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2010.03.051

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title = "A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions",

abstract = "A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.",

author = "Barange, {Deepak Kumar} and Raju, {B. Rama} and Veerababurao Kavala and Kuo, {Chun Wei} and Tu, {Yu Chen} and Yao, {Ching Fa}",

note = "Funding Information: Financial support of this work by National Science Council of the Republic of China and National Taiwan Normal University is gratefully acknowledged. ",

year = "2010",

month = may,

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doi = "10.1016/j.tet.2010.03.051",

language = "English",

volume = "66",

pages = "3754--3760",

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T1 - A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

AU - Barange, Deepak Kumar

AU - Raju, B. Rama

AU - Kavala, Veerababurao

AU - Kuo, Chun Wei

AU - Tu, Yu Chen

AU - Yao, Ching Fa

N1 - Funding Information: Financial support of this work by National Science Council of the Republic of China and National Taiwan Normal University is gratefully acknowledged.

PY - 2010/5/22

Y1 - 2010/5/22

N2 - A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.

AB - A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.

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DO - 10.1016/j.tet.2010.03.051

M3 - Article

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SN - 0040-4020

VL - 66

SP - 3754

EP - 3760

JO - Tetrahedron

JF - Tetrahedron

IS - 21

ER -

A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Abstract

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CCDC 725385: Experimental Crystal Structure Determination

CCDC 725383: Experimental Crystal Structure Determination

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A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Abstract

ASJC Scopus subject areas

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Datasets

CCDC 725385: Experimental Crystal Structure Determination

CCDC 725383: Experimental Crystal Structure Determination

Cite this