Abstract
A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.
| Original language | English |
|---|---|
| Pages (from-to) | 3754-3760 |
| Number of pages | 7 |
| Journal | Tetrahedron |
| Volume | 66 |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 2010 May 22 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Barange, D. K., Raju, B. R., Kavala, V., Kuo, C. W., Tu, Y. C., & Yao, C. F. (2010). A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. Tetrahedron, 66(21), 3754-3760. https://doi.org/10.1016/j.tet.2010.03.051