A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Deepak Kumar Barange; B. Rama Raju; Veerababurao Kavala; Chun Wei Kuo; Yu Chen Tu; Ching Fa Yao

doi:10.1016/j.tet.2010.03.051

A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Deepak Kumar Barange, B. Rama Raju, Veerababurao Kavala, Chun Wei Kuo, Yu Chen Tu, Ching Fa Yao

Department of Chemistry

Research output: Contribution to journal › Article

26 Citations (Scopus)

Abstract

A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.

Original language	English
Pages (from-to)	3754-3760
Number of pages	7
Journal	Tetrahedron
Volume	66
Issue number	21
DOIs	https://doi.org/10.1016/j.tet.2010.03.051
Publication status	Published - 2010 May 22

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Microwave irradiation

Silica Gel

Microwaves

Isomers

Chemical activation

Derivatives

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Cite this

Barange, D. K., Raju, B. R., Kavala, V., Kuo, C. W., Tu, Y. C., & Yao, C. F. (2010). A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. Tetrahedron, 66(21), 3754-3760. https://doi.org/10.1016/j.tet.2010.03.051

A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. / Barange, Deepak Kumar; Raju, B. Rama; Kavala, Veerababurao; Kuo, Chun Wei; Tu, Yu Chen; Yao, Ching Fa.

In: Tetrahedron, Vol. 66, No. 21, 22.05.2010, p. 3754-3760.

Research output: Contribution to journal › Article

Barange, DK, Raju, BR, Kavala, V, Kuo, CW, Tu, YC & Yao, CF 2010, 'A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions', Tetrahedron, vol. 66, no. 21, pp. 3754-3760. https://doi.org/10.1016/j.tet.2010.03.051

Barange DK, Raju BR, Kavala V, Kuo CW, Tu YC, Yao CF. A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. Tetrahedron. 2010 May 22;66(21):3754-3760. https://doi.org/10.1016/j.tet.2010.03.051

Barange, Deepak Kumar ; Raju, B. Rama ; Kavala, Veerababurao ; Kuo, Chun Wei ; Tu, Yu Chen ; Yao, Ching Fa. / A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. In: Tetrahedron. 2010 ; Vol. 66, No. 21. pp. 3754-3760.

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10.1016/j.tet.2010.03.051