A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions

Deepak Kumar Barange, B. Rama Raju, Veerababurao Kavala, Chun Wei Kuo, Yu Chen Tu, Ching Fa Yao

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A convenient one-pot two-step procedure for the synthesis of hydroxyiminodihydrobenzofurans assisted by microwave irradiation in presence of silica gel is described herein. Cyclic 1,3-dicarbonyl compounds reacted smoothly with various nitroolefins to furnish hydroxyiminodihydrobenzofuran derivatives as the mixture of E and Z isomers. Clean reaction conditions, no work-up procedure, easy isolation and good yields of the products are the salient features of the methodology.

Original languageEnglish
Pages (from-to)3754-3760
Number of pages7
JournalTetrahedron
Volume66
Issue number21
DOIs
Publication statusPublished - 2010 May 22

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Microwave irradiation
Silica Gel
Microwaves
Isomers
Chemical activation
Derivatives

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. / Barange, Deepak Kumar; Raju, B. Rama; Kavala, Veerababurao; Kuo, Chun Wei; Tu, Yu Chen; Yao, Ching Fa.

In: Tetrahedron, Vol. 66, No. 21, 22.05.2010, p. 3754-3760.

Research output: Contribution to journalArticle

Barange, Deepak Kumar ; Raju, B. Rama ; Kavala, Veerababurao ; Kuo, Chun Wei ; Tu, Yu Chen ; Yao, Ching Fa. / A mild and convenient one-pot two-step synthesis of hydroxy- iminodihydrobenzofurans mediated by silica gel under microwave activation conditions. In: Tetrahedron. 2010 ; Vol. 66, No. 21. pp. 3754-3760.
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