A micro GC detector array based on chemiresistors employing various surface functionalized monolayer-protected gold nanoparticles

Rih Sheng Jian, Rui Xuan Huang, Chia-Jung Lu

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Aspects of the design, fabrication, and characterization of a chemiresistor type of microdetector for use in conjunction with gas chromatograph are described. The detector was manufactured on silicon chips using microelectromechanical systems (MEMS) technology. Detection was based on measuring changes in resistance across a film comprised of monolayer-protected gold nanoclusters (MPCs). When chromatographic separated molecules entered the detector cell, the MPC film absorbed vapor and undergoes swelling, then the resistance changes accordingly. Thiolates were used as ligand shells to encapsulate the nano-gold core and to manipulate the selectivity of the detector array. The dimensions of the μ-detector array were 14(L) × 3.9(W) × 1.2(H) mm. Mixtures of eight volatile organic compounds with different functional groups and volatility were tested to characterize the selectivity of the μ-detector array. The detector responses were rapid, reversible, and linear for all of the tested compounds. The detection limits ranged from 2 to 111 ng, and were related to both the compound volatility and the selectivity of the surface ligands on the gold nanoparticles. Design and operation parameters such as flow rate, detector temperature, and width of the micro-fluidic channel were investigated. Reduction of the detector temperature resulted in improved sensitivity due to increased absorption. When a wider flow channel was used, the signal-to-noise ratio was improved due to the larger sensing area. The extremely low power consumption and small size makes this μ-detector array potentially useful for the development of integrated μ-GC.

Original languageEnglish
Pages (from-to)160-167
Number of pages8
JournalTalanta
Volume88
DOIs
Publication statusPublished - 2012 Jan 15

Fingerprint

Gold
Nanoparticles
Monolayers
Detectors
Volatilization
Ligands
Volatile Organic Compounds
Temperature
Signal-To-Noise Ratio
Silicon
Nanoclusters
Limit of Detection
Gases
Technology
Fluidics
Channel flow
Functional groups
MEMS
Swelling
Signal to noise ratio

Keywords

  • Chemiresistor
  • MEMS
  • Vapor sensor
  • Volatile organic compounds
  • micro-GC

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

A micro GC detector array based on chemiresistors employing various surface functionalized monolayer-protected gold nanoparticles. / Jian, Rih Sheng; Huang, Rui Xuan; Lu, Chia-Jung.

In: Talanta, Vol. 88, 15.01.2012, p. 160-167.

Research output: Contribution to journalArticle

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