A genetic model for cardiac pattern formation and cell fate determination

Wendy K. Lockwood; Margaret Liu; Ming Tsan Su; Rolf Bodmer

doi:10.1201/b14019

A genetic model for cardiac pattern formation and cell fate determination

Wendy K. Lockwood, Margaret Liu, Ming Tsan Su, Rolf Bodmer

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Citations (Scopus)

Abstract

The Drosophila heart shares many embryological and molecular similarities with those of vertebrates despite the morphological differences of the final products. For example, their mesodermal origin and initial assembly into a linear heart tube are comparable in many respects. Moreover, numerous gene functions have been identified that are utilized by both vertebrates and Drosophila for the specification and differentiation of the heart progenitor cells. Because of the simplicity in structure and the wealth of genetic tools available, the Drosophila heart has emerged as a pioneering model system for elucidating the molecular basis of heart development.

Original language	English
Title of host publication	Genetic Models in Cardiorespiratory Biology
Publisher	CRC Press
Pages	179-202
Number of pages	24
ISBN (Electronic)	9780824746056
ISBN (Print)	9780824705121
DOIs	https://doi.org/10.1201/b14019
Publication status	Published - 2001 Jan 1
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology
General Medicine

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10.1201/b14019

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A genetic model for cardiac pattern formation and cell fate determination

Abstract

ASJC Scopus subject areas

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