A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control

Wei Ming Chen, Herming Chiueh, Tsan Jieh Chen, Chia Lun Ho, Chi Jeng, Shun Ting Chang, Ming Dou Ker, Chun-Yu Lin, Ya Chun Huang, Chia Wei Chou, Tsun Yuan Fan, Ming Seng Cheng, Sheng Fu Liang, Tzu Chieh Chien, Sih Yen Wu, Yu Lin Wang, Fu Zen Shaw, Yu Hsing Huang, Chia Hsiang Yang, Jin Chern ChiouChih Wei Chang, Lei Chun Chou, Chung Yu Wu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

47 Citations (Scopus)

Abstract

Epilepsy is one of the most common neurological disorders. Around 1% of the world's population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and effective stimulation for real-time seizure control are still unavailable. In this paper, a fully integrated 8-channel closed-loop seizure-control SoC with entropy-and-spectrum- aided seizure detection and adaptive neural stimulation is presented. This chip is powered wirelessly, aiming for implantable devices. The functionality of the fabricated chip is verified in animal tests.

Original languageEnglish
Title of host publication2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers
Pages286-287
Number of pages2
DOIs
Publication statusPublished - 2013 Apr 29
Event2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013 - San Francisco, CA, United States
Duration: 2013 Feb 172013 Feb 21

Publication series

NameDigest of Technical Papers - IEEE International Solid-State Circuits Conference
Volume56
ISSN (Print)0193-6530

Other

Other2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013
CountryUnited States
CitySan Francisco, CA
Period13/2/1713/2/21

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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    Chen, W. M., Chiueh, H., Chen, T. J., Ho, C. L., Jeng, C., Chang, S. T., Ker, M. D., Lin, C-Y., Huang, Y. C., Chou, C. W., Fan, T. Y., Cheng, M. S., Liang, S. F., Chien, T. C., Wu, S. Y., Wang, Y. L., Shaw, F. Z., Huang, Y. H., Yang, C. H., ... Wu, C. Y. (2013). A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control. In 2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers (pp. 286-287). [6487737] (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 56). https://doi.org/10.1109/ISSCC.2013.6487737