A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions

Ko Wei Chen, Siang En Syu, Yeong Jiunn Jang, Wenwei Lin

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

An efficient and mild synthesis of trisubstituted furans, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides, is described. The strategy employs the intramolecular Wittig protocol as a key step to install the crucial furan ring, leading to a wide variety of highly functional furans in one step.

Original languageEnglish
Pages (from-to)2098-2106
Number of pages9
JournalOrganic and Biomolecular Chemistry
Volume9
Issue number7
DOIs
Publication statusPublished - 2011 Apr 7

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Furans
furans
Ketones
Chlorides
ketones
chlorides
rings
synthesis
tri-n-butylphosphine
furan

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions. / Chen, Ko Wei; Syu, Siang En; Jang, Yeong Jiunn; Lin, Wenwei.

In: Organic and Biomolecular Chemistry, Vol. 9, No. 7, 07.04.2011, p. 2098-2106.

Research output: Contribution to journalArticle

Chen, Ko Wei ; Syu, Siang En ; Jang, Yeong Jiunn ; Lin, Wenwei. / A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions. In: Organic and Biomolecular Chemistry. 2011 ; Vol. 9, No. 7. pp. 2098-2106.
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