A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions

Ko Wei Chen, Siang En Syu, Yeong Jiunn Jang, Wenwei Lin

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

An efficient and mild synthesis of trisubstituted furans, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides, is described. The strategy employs the intramolecular Wittig protocol as a key step to install the crucial furan ring, leading to a wide variety of highly functional furans in one step.

Original languageEnglish
Pages (from-to)2098-2106
Number of pages9
JournalOrganic and Biomolecular Chemistry
Volume9
Issue number7
DOIs
Publication statusPublished - 2011 Apr 7

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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