A Dynamic Data Correction Method for Enhancing Resolving Power of Integrated Spectra in Spectroscopic Analysis

Chih Hao Hsiao, Yin Hung Lai, Shu Yun Kuo, Yi Hong Cai, Cheng Huang Lin, Yi Sheng Wang

Research output: Contribution to journalArticlepeer-review

Abstract

A dynamic data correction method embedded in the process of data acquisition improves spectral quality. The method minimizes the impact of random errors in spectroscopic measurements by correcting peak positions in every single-scan spectrum. The method is fast enough to facilitate online data correction. The integration of corrected spectra improves resolving power and signal-to-noise ratio. The correction method can apply to most analytical spectra. In mass spectrometry and Raman spectroscopy, observations show that it improved the average resolving power by roughly 40-150% and revealed unresolved spectral features.

Original languageEnglish
Pages (from-to)12763-12768
Number of pages6
JournalAnalytical Chemistry
Volume92
Issue number19
DOIs
Publication statusPublished - 2020 Oct 6

ASJC Scopus subject areas

  • Analytical Chemistry

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