A dual-mode radio frequency DNA sensor

J. H. Chien, C. H. Chang, Y. F. Hsieh, D. S. Lee, L. S. Kuo, C. H. Yang, C. R. Yang, W. P. Chou, P. H. Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Different from traditional detection methods which were expensive and time consuming for biochemical analyses, a DNA chip assay by using gold nanoparticles (AuNPs) immunological amplification methods and radio frequency techniques was applied to detect DNA sequences rapidly and conveniently. First the capture DNA (cDNA) was immobilized to the substrate on which the LC shunt located. Then the target DNA (tDNA) and probe DNA (pDNA) with AuNP at the 3' end were added to form AuNP-linking structures. Furthermore, the SU and S21 curves of the biosensors changed due to the AuNP-linking structures between the interdigital and meander waveguides. The changes in S11 and S21 determined whether the tDNA existed. Due to the dual-mode design of the DNA sensors, this platform has a potential for multisample detection. The study provided an alternatively simple, fast and convenient solution for biochemical detection

Original languageEnglish
Title of host publicationProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
Pages532-536
Number of pages5
DOIs
Publication statusPublished - 2007 Aug 28
Event2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 - Bangkok, Thailand
Duration: 2007 Jan 162007 Jan 19

Publication series

NameProceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

Other

Other2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
CountryThailand
CityBangkok
Period07/1/1607/1/19

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Keywords

  • Diagnostic detection
  • Gold nanoparticles
  • Radio frequency
  • Self-assembly

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Computer Science Applications
  • Electrical and Electronic Engineering

Cite this

Chien, J. H., Chang, C. H., Hsieh, Y. F., Lee, D. S., Kuo, L. S., Yang, C. H., Yang, C. R., Chou, W. P., & Chen, P. H. (2007). A dual-mode radio frequency DNA sensor. In Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 (pp. 532-536). [4160378] (Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007). https://doi.org/10.1109/NEMS.2007.352075