Abstract
A convenient one-pot preparation of 2-methyl-3-(phenylthiomethyl)quinolines from Morita-Baylis-Hillman adducts via conjugate addition of thiols followed by reductive cyclization with Fe/AcOH was developed. The 2-methyl-3- (phenylthiomethyl)quinolines were transformed into 2-methyl-3- (phenylsulfonylmethyl)quinolines via m-CPBA-mediated oxidation
| Original language | English |
|---|---|
| Pages (from-to) | 5081-5094 |
| Number of pages | 14 |
| Journal | Molecules |
| Volume | 17 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2012 May 1 |
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Keywords
- Fe/AcOH
- Morita-Baylis-Hillman adducts
- One-pot procedure
- Quinolines
- Reductive cyclization
ASJC Scopus subject areas
- Organic Chemistry
- Medicine(all)
Cite this
A convenient one-pot preparation of 2-methyl-3-(phenylthiomethyl) quinolines from morita-baylis-hillman adducts and their oxidation to the corresponding sulfones. / Ramesh, Chintakunta; Lei, Po Min; Kavala, Veerababurao; Kuo, Chun Wei; Yao, Ching Fa.
In: Molecules, Vol. 17, No. 5, 01.05.2012, p. 5081-5094.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A convenient one-pot preparation of 2-methyl-3-(phenylthiomethyl) quinolines from morita-baylis-hillman adducts and their oxidation to the corresponding sulfones
AU - Ramesh, Chintakunta
AU - Lei, Po Min
AU - Kavala, Veerababurao
AU - Kuo, Chun Wei
AU - Yao, Ching Fa
PY - 2012/5/1
Y1 - 2012/5/1
N2 - A convenient one-pot preparation of 2-methyl-3-(phenylthiomethyl)quinolines from Morita-Baylis-Hillman adducts via conjugate addition of thiols followed by reductive cyclization with Fe/AcOH was developed. The 2-methyl-3- (phenylthiomethyl)quinolines were transformed into 2-methyl-3- (phenylsulfonylmethyl)quinolines via m-CPBA-mediated oxidation
AB - A convenient one-pot preparation of 2-methyl-3-(phenylthiomethyl)quinolines from Morita-Baylis-Hillman adducts via conjugate addition of thiols followed by reductive cyclization with Fe/AcOH was developed. The 2-methyl-3- (phenylthiomethyl)quinolines were transformed into 2-methyl-3- (phenylsulfonylmethyl)quinolines via m-CPBA-mediated oxidation
KW - Fe/AcOH
KW - Morita-Baylis-Hillman adducts
KW - One-pot procedure
KW - Quinolines
KW - Reductive cyclization
UR - http://www.scopus.com/inward/record.url?scp=84861492177&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861492177&partnerID=8YFLogxK
U2 - 10.3390/molecules17055081
DO - 10.3390/molecules17055081
M3 - Article
C2 - 22555297
AN - SCOPUS:84861492177
VL - 17
SP - 5081
EP - 5094
JO - Molecules
JF - Molecules
SN - 1420-3049
IS - 5
ER -