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• 2020

  Copper-catalysed synthesis of 3-hydroxyisoindolin-1-ones from benzylcyanide 2-iodobenzamides

  Kavala, V., Wang, C. Y., Wang, C. C., Patil, P. B., Fang, C. C., Kuo, C. W. & Yao, C. F., 2020 Jan 1, In: Organic and Biomolecular Chemistry. 18, 5, p. 988-998 11 p.

  Research output: Contribution to journal › Article › peer-review

  • benzyl cyanide
  • cyanides
  • cesium carbonate
  • Copper
  • Derivatives
  1 Citation (Scopus)

• Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation

  Chiu, Y. J., Lin, S. A., Chen, W. L., Lin, T. H., Lin, C. H., Yao, C. F., Lin, W., Wu, Y. R., Chang, K. H., Lee-Chen, G. J. & Chen, C. M., 2020 Dec, In: Aging. 12, 23, p. 23619-23646 28 p.

  Research output: Contribution to journal › Article › peer-review

  • polyglutamine
  • N-(4-hydroxyphenyl)arachidonylamide
  • Microglia
  • Interleukin-1
  • 4-aminophenol

• Synthesis of Pyrido[2,3-b]indoles via Brønsted-Acid-Promoted Decarboxylative Annulation of 3-Bromopropenals and Ethyl 2-Amino-1H-indole-3-carboxylates

  Yang, T. H., Kavala, V., Kuo, C. W. & Yao, C. F., 2020 Jul 1, In: Asian Journal of Organic Chemistry. 9, 7, p. 1053-1058 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbolines
  • Indoles
  • indole
  • Derivatives
  • Acids
  1 Citation (Scopus)
• 2019

  A Synthetic Strategy for the Construction of Functionalized Triphenylene Frameworks via Palladium Catalyzed Intramolecular Annulation/Decyanogenative C-H Bond Alkenylation

  Ichake, S. S., Villuri, B. K., Reddy, S. R., Kavala, V. & Yao, C. F., 2019 Jan 1, In: Organic Letters. 21, 7, p. 2256-2260 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Alkenylation
  • triphenylene
  • benzyl cyanide
  • Palladium
  • cyanides
  2 Citations (Scopus)

• Indole compound NC009-1 augments APOE and TRKA in Alzheimer's disease cell and mouse models for neuroprotection and cognitive improvement

  Chen, Y. C., Chiu, Y. J., Lin, C. H., Hsu, W. C., Wu, J. L., Huang, C. H., Lin, C. W., Yao, C. F., Huang, H. J., Lo, Y. S., Chen, C. M., Wu, Y. R., Chang, K. H., Lee-Chen, G. J. & Hsieh-Li, H. M., 2019 Jan 1, In: Journal of Alzheimer's Disease. 67, 2, p. 737-756 20 p.

  Research output: Contribution to journal › Article › peer-review

  • tropomyosin kinase
  • Low Density Lipoprotein Receptor-Related Protein-1
  • indole
  • Neuroprotection
  • Alzheimer Disease
  4 Citations (Scopus)

• Microwave-Assisted Ruthenium(II)-Catalyzed C−H/N−O Activation of N-Methoxybenzamides with Alkynylsulfane

  Sarathkumar, S., Kavala, V. & Yao, C. F., 2019 Oct 1, In: Asian Journal of Organic Chemistry. 8, 10, p. 1830-1833 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ruthenium
  • Chemical activation
  • Microwaves
  • Derivatives
  3 Citations (Scopus)

• Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models

  Wei, P. C., Lee-Chen, G. J., Chen, C. M., Wu, Y. R., Chen, Y. J., Lin, J. L., Lo, Y. S., Yao, C. F. & Chang, K. H., 2019, In: Oxidative medicine and cellular longevity. 2019, 5074367.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • indole
  • Neuroprotection
  • Dopaminergic Neurons
  • Parkinson Disease
  • Derivatives
  9 Citations (Scopus)

• Synthesis of Polysubstituted Cyclopentene and Cyclopenta[ b]carbazole Analogues from Unsymmetrical 4-Arylidene-3,6-diarylhex-2-en-5-ynal and Indole Derivatives via an Iodine Mediated Electrocyclization Reaction

  Bandi, V., Kavala, V., Konala, A., Hsu, C. H., Villuri, B. K., Reddy, S. R., Lin, L., Kuo, C. W. & Yao, C. F., 2019 Mar 15, In: Journal of Organic Chemistry. 84, 6, p. 3036-3044 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclopentanes
  • carbazole
  • Indoles
  • indole
  • 7-methylindole
  2 Citations (Scopus)
• 2018

  A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells

  Hsieh, C. H., Wang, J. P., Chiu, C. C., Liu, C. Y., Yao, C. F. & Fang, K., 2018 Jan 1, In: Apoptosis. 23, 1

  Research output: Contribution to journal › Article › peer-review

  • Triazoles
  • Tumors
  • Cells
  • Reactive Oxygen Species
  • Lung Neoplasms
  6 Citations (Scopus)

• Copper-Catalyzed Cascade Synthesis of 2-Aryl-3-cyanobenzofuran and Dibenzo[ b, f]oxepine-10-carbonitrile Derivatives

  Villuri, B. K., Ichake, S. S., Reddy, S. R., Kavala, V., Bandi, V., Kuo, C. W. & Yao, C. F., 2018 Sep 7, In: Journal of Organic Chemistry. 83, 17, p. 10241-10247 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxepins
  • Hydroxylation
  • Copper
  • Condensation
  • Benzaldehydes
  8 Citations (Scopus)

• Synthesis of 1,2,3-Fused Indole Polyheterocycles by Copper-Catalyzed Cascade Reaction

  Kavala, V., Yang, Z., Konala, A., Yang, T. H., Kuo, C. W., Ruan, J. Y. & Yao, C. F., 2018 Mar 14, In: European Journal of Organic Chemistry. 2018, 10, p. 1241-1247 7 p.

  Research output: Contribution to journal › Article › peer-review

  • indoles
  • cyanides
  • indole
  • Cyanides
  • reaction time
  8 Citations (Scopus)

• The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice

  Chen, C. M., Chen, W. L., Hung, C. T., Lin, T. H., Chao, C. Y., Lin, C. H., Wu, Y. R., Chang, K. H., Yao, C. F., Lee-Chen, G. J., Su, M. T. & Hsieh-Li, H. M., 2018 Jul 1, In: NeuroToxicology. 67, p. 259-269 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Spinocerebellar Ataxia 17
  • TATA-Box Binding Protein
  • indole
  • Neuronal Outgrowth
  • Agglomeration
  11 Citations (Scopus)