Find Research outputs

Search results

• 2020

  Copper-catalysed synthesis of 3-hydroxyisoindolin-1-ones from benzylcyanide 2-iodobenzamides

  Kavala, V., Wang, C. Y., Wang, C. C., Patil, P. B., Fang, C. C., Kuo, C. W. & Yao, C. F., 2020 Jan 1, In: Organic and Biomolecular Chemistry. 18, 5, p. 988-998 11 p.

  Research output: Contribution to journal › Article › peer-review

  • benzyl cyanide
  • cyanides
  • cesium carbonate
  • Copper
  • Derivatives
  1 Citation (Scopus)

• Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation

  Chiu, Y. J., Lin, S. A., Chen, W. L., Lin, T. H., Lin, C. H., Yao, C. F., Lin, W., Wu, Y. R., Chang, K. H., Lee-Chen, G. J. & Chen, C. M., 2020 Dec, In: Aging. 12, 23, p. 23619-23646 28 p.

  Research output: Contribution to journal › Article › peer-review

  • polyglutamine
  • N-(4-hydroxyphenyl)arachidonylamide
  • Microglia
  • Interleukin-1
  • 4-aminophenol

• Synthesis of Pyrido[2,3-b]indoles via Brønsted-Acid-Promoted Decarboxylative Annulation of 3-Bromopropenals and Ethyl 2-Amino-1H-indole-3-carboxylates

  Yang, T. H., Kavala, V., Kuo, C. W. & Yao, C. F., 2020 Jul 1, In: Asian Journal of Organic Chemistry. 9, 7, p. 1053-1058 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbolines
  • Indoles
  • indole
  • Derivatives
  • Acids
  1 Citation (Scopus)
• 2019

  A Synthetic Strategy for the Construction of Functionalized Triphenylene Frameworks via Palladium Catalyzed Intramolecular Annulation/Decyanogenative C-H Bond Alkenylation

  Ichake, S. S., Villuri, B. K., Reddy, S. R., Kavala, V. & Yao, C. F., 2019 Jan 1, In: Organic Letters. 21, 7, p. 2256-2260 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Alkenylation
  • triphenylene
  • benzyl cyanide
  • Palladium
  • cyanides
  2 Citations (Scopus)

• Indole compound NC009-1 augments APOE and TRKA in Alzheimer's disease cell and mouse models for neuroprotection and cognitive improvement

  Chen, Y. C., Chiu, Y. J., Lin, C. H., Hsu, W. C., Wu, J. L., Huang, C. H., Lin, C. W., Yao, C. F., Huang, H. J., Lo, Y. S., Chen, C. M., Wu, Y. R., Chang, K. H., Lee-Chen, G. J. & Hsieh-Li, H. M., 2019 Jan 1, In: Journal of Alzheimer's Disease. 67, 2, p. 737-756 20 p.

  Research output: Contribution to journal › Article › peer-review

  • tropomyosin kinase
  • Low Density Lipoprotein Receptor-Related Protein-1
  • indole
  • Neuroprotection
  • Alzheimer Disease
  4 Citations (Scopus)

• Microwave-Assisted Ruthenium(II)-Catalyzed C−H/N−O Activation of N-Methoxybenzamides with Alkynylsulfane

  Sarathkumar, S., Kavala, V. & Yao, C. F., 2019 Oct 1, In: Asian Journal of Organic Chemistry. 8, 10, p. 1830-1833 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ruthenium
  • Chemical activation
  • Microwaves
  • Derivatives
  3 Citations (Scopus)

• Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models

  Wei, P. C., Lee-Chen, G. J., Chen, C. M., Wu, Y. R., Chen, Y. J., Lin, J. L., Lo, Y. S., Yao, C. F. & Chang, K. H., 2019, In: Oxidative medicine and cellular longevity. 2019, 5074367.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • indole
  • Neuroprotection
  • Dopaminergic Neurons
  • Parkinson Disease
  • Derivatives
  9 Citations (Scopus)

• Synthesis of Polysubstituted Cyclopentene and Cyclopenta[ b]carbazole Analogues from Unsymmetrical 4-Arylidene-3,6-diarylhex-2-en-5-ynal and Indole Derivatives via an Iodine Mediated Electrocyclization Reaction

  Bandi, V., Kavala, V., Konala, A., Hsu, C. H., Villuri, B. K., Reddy, S. R., Lin, L., Kuo, C. W. & Yao, C. F., 2019 Mar 15, In: Journal of Organic Chemistry. 84, 6, p. 3036-3044 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclopentanes
  • carbazole
  • Indoles
  • indole
  • 7-methylindole
  2 Citations (Scopus)
• 2017

  A Copper-Catalyzed Cascade Approach for the Synthesis of Dibenzo[b,f]1,8-naphthyridine Derivatives

  Villuri, B. K., Konala, A., Kavala, V., Kotipalli, T., Kuo, C. W. & Yao, C. F., 2017 Sep 18, In: Advanced Synthesis and Catalysis. 359, 18, p. 3142-3153 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Naphthyridines
  • Copper
  • Derivatives
  • Alkynes
  • Nitriles
  5 Citations (Scopus)

• A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres

  Ni, Y. L., Hsieh, C. H., Kim, S. H., Wang, J. P., Su, C. L., Yao, C. F. & Fang, K., 2017 Oct 1, In: Apoptosis. 22, 10, p. 1235-1245 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cells
  • 3-((7-ethyl-1H-indol-3-yl)-methyl)-2-methylquinoline
  • Lung Neoplasms
  • Tumors
  • Mitochondria
  1 Citation (Scopus)

• Palladium-catalyzed tandem C-H functionalization/cyclization strategy for the synthesis of 5-hydroxybenzofuran derivatives

  Ichake, S. S., Konala, A., Kavala, V., Kuo, C. W. & Yao, C. F., 2017 Jan 6, In: Organic Letters. 19, 1, p. 54-57 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclization
  • alkynes
  • Alkynes
  • Palladium
  • quinones
  19 Citations (Scopus)

• Regioselective switching approach for the synthesis of α and δ carboline derivatives

  Yang, T. H., Kuo, C. W., Kavala, V., Konala, A., Huang, C. Y. & Yao, C. F., 2017, In: Chemical Communications. 53, 10, p. 1676-1679 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbolines
  • Oximes
  • Derivatives
  • Esters
  • Metals
  14 Citations (Scopus)

• Synthesis of Benzopyridoindolone Derivatives via a One-Pot Copper Catalyzed Tandem Reaction of 2-Iodobenzamide Derivatives and 2-Iodobenzylcyanides

  Kavala, V., Yang, Z., Konala, A., Huang, C. Y., Kuo, C. W. & Yao, C. F., 2017 Jul 21, In: Journal of Organic Chemistry. 82, 14, p. 7280-7286 7 p.

  Research output: Contribution to journal › Article › peer-review

  • indole
  • Copper
  • Pyridones
  • Derivatives
  • Thiophenes
  12 Citations (Scopus)

• Synthesis of Biologically Active Indenoisoquinoline Derivatives via a One-Pot Copper(II)-Catalyzed Tandem Reaction

  Huang, C. Y., Kavala, V., Kuo, C. W., Konala, A., Yang, T. H. & Yao, C. F., 2017 Feb 17, In: Journal of Organic Chemistry. 82, 4, p. 1961-1968 8 p.

  Research output: Contribution to journal › Article › peer-review

  • NSC 314622
  • cesium carbonate
  • NSC 724998
  • 1,2-indanedione
  • cupric chloride
  22 Citations (Scopus)

• Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines

  Bandi, V., Kavala, V., Hsu, C. H., Konala, A., Villuri, B. K., Kotipalli, T., Kuo, C. W. & Yao, C. F., 2017, In: RSC Advances. 7, 74, p. 46704-46712 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pyridines
  • Pyridine
  • 1,3-butadiene
  • Styrene
  • Butadiene
  2 Citations (Scopus)

• The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1

  Chang, K. H., Lin, C. H., Chen, H. C., Huang, H. Y., Chen, S. L., Lin, T. H., Ramesh, C., Huang, C. C., Fung, H. C., Wu, Y. R., Huang, H. J., Lee-Chen, G. J., Hsieh-Li, H. M. & Yao, C. F., 2017 Jan 1, In: CNS Neuroscience and Therapeutics. 23, 1, p. 45-56 12 p.

  Research output: Contribution to journal › Article › peer-review

  • indole
  • fluorescent protein 583
  • Neuronal Outgrowth
  • Alzheimer Disease
  • Solubility
  10 Citations (Scopus)

• Using gene expression database to uncover biology functions of 1,4-disubstituted 1,2,3-triazole analogues synthesized via a copper (I)-catalyzed reaction

  Su, C. L., Tseng, C. L., Ramesh, C., Liu, H. S., Huang, C. Y. F. & Yao, C. F., 2017, In: European Journal of Medicinal Chemistry. 132, p. 90-107 18 p.

  Research output: Contribution to journal › Article › peer-review

  • N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea
  • Cytotoxicity
  • Triazoles
  • Gene expression
  • Cycloaddition
  16 Citations (Scopus)