2-Cyanoethylzinc iodide: A new reagent with reactivity umpolung

Ming Chang P. Yeh; Paul Knochel

doi:10.1016/S0040-4039(00)87890-9

2-Cyanoethylzinc iodide: A new reagent with reactivity umpolung

Ming Chang P. Yeh^*, Paul Knochel

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

80 Citations (Scopus)

Abstract

2-Cyanoethylzinc iodide 1 generated in over 90% yield from 3-iodopropionitrile and zinc in THF can be transmetallated to the copper and titanium derivatives 3 and 4 which react in good yields, respectively, with acyl chlorides, enones, allylic halides and benzaldehyde.

Original language	English
Pages (from-to)	2395-2396
Number of pages	2
Journal	Tetrahedron Letters
Volume	29
Issue number	20
DOIs	https://doi.org/10.1016/S0040-4039(00)87890-9
Publication status	Published - 1988
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)87890-9

Cite this

@article{06a39316d0ad47fa920d85e32b459110,

title = "2-Cyanoethylzinc iodide: A new reagent with reactivity umpolung",

abstract = "2-Cyanoethylzinc iodide 1 generated in over 90% yield from 3-iodopropionitrile and zinc in THF can be transmetallated to the copper and titanium derivatives 3 and 4 which react in good yields, respectively, with acyl chlorides, enones, allylic halides and benzaldehyde.",

author = "Yeh, {Ming Chang P.} and Paul Knochel",

year = "1988",

doi = "10.1016/S0040-4039(00)87890-9",

language = "English",

volume = "29",

pages = "2395--2396",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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T1 - 2-Cyanoethylzinc iodide

T2 - A new reagent with reactivity umpolung

AU - Yeh, Ming Chang P.

AU - Knochel, Paul

PY - 1988

Y1 - 1988

N2 - 2-Cyanoethylzinc iodide 1 generated in over 90% yield from 3-iodopropionitrile and zinc in THF can be transmetallated to the copper and titanium derivatives 3 and 4 which react in good yields, respectively, with acyl chlorides, enones, allylic halides and benzaldehyde.

AB - 2-Cyanoethylzinc iodide 1 generated in over 90% yield from 3-iodopropionitrile and zinc in THF can be transmetallated to the copper and titanium derivatives 3 and 4 which react in good yields, respectively, with acyl chlorides, enones, allylic halides and benzaldehyde.

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UR - http://www.scopus.com/inward/citedby.url?scp=0000399484&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)87890-9

DO - 10.1016/S0040-4039(00)87890-9

M3 - Article

AN - SCOPUS:0000399484

SN - 0040-4039

VL - 29

SP - 2395

EP - 2396

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 20

ER -

2-Cyanoethylzinc iodide: A new reagent with reactivity umpolung

Abstract

ASJC Scopus subject areas

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