氨基啡林對大白鼠舌肌呼吸活動的影響

慧明(Hwei-Ming Chuang) 莊; 忠信(long-Shin Wu) 吳; 基礎(Ji-Chuu Hwang) 黃

doi:10.29812/BBNTNU.199612.0006

氨基啡林對大白鼠舌肌呼吸活動的影響

莊慧明(Hwei-Ming Chuang), 吳忠信(long-Shin Wu), 黃基礎(Ji-Chuu Hwang)

Department of Life Science

Research output: Contribution to journal › Article › peer-review

Abstract

The purpose of the present study was to evaluate the response of genioglossus muscle (GG) to bolus injection of aminophvlline (AP). Adult rats were anesthetized with urethane. Electromyograms (EMG) of the GG and the diaphragm (Dia) were observed. Blood pressure was monitored. GG EMG increased to 144% (p＜.0.01) and Dia EMG enhanced to 111% in response to 4 mg/kg of AP. With high dose of AP treatment (32 mg/kg b.w.), GG EMG increased to 188% (p＜0.01) while Dia EMG argumented to 122% (p＜0.01). After peak response, Dia activity was gradually recovered to normal level. Yet, GG EMG was still higher than that of control 30 minutes alter high dose of AP treatment. These results indicate that Dia and GG activities were enhanced by AP and that enhancement of GG response is much more than that of the Dia.

Original language	Chinese (Traditional)
Pages (from-to)	141-148
Number of pages	8
Journal	師大生物學報
Volume	31
Issue number	2
DOIs	https://doi.org/10.29812/BBNTNU.199612.0006
Publication status	Published - 1996

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10.29812/BBNTNU.199612.0006

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@article{d22c7775e4614ace9762522dc9efa78d,

title = "氨基啡林對大白鼠舌肌呼吸活動的影響",

abstract = "The purpose of the present study was to evaluate the response of genioglossus muscle (GG) to bolus injection of aminophvlline (AP). Adult rats were anesthetized with urethane. Electromyograms (EMG) of the GG and the diaphragm (Dia) were observed. Blood pressure was monitored. GG EMG increased to 144% (p＜.0.01) and Dia EMG enhanced to 111% in response to 4 mg/kg of AP. With high dose of AP treatment (32 mg/kg b.w.), GG EMG increased to 188% (p＜0.01) while Dia EMG argumented to 122% (p＜0.01). After peak response, Dia activity was gradually recovered to normal level. Yet, GG EMG was still higher than that of control 30 minutes alter high dose of AP treatment. These results indicate that Dia and GG activities were enhanced by AP and that enhancement of GG response is much more than that of the Dia.",

keywords = "氨基啡林, 橫膈, 舌肌, 肌電圖, 呼吸活動, 大白鼠, aminophylline, diaphragm, genioglossus muscle, electromyogram, respiratory activity, rat",

author = "莊, {慧明(Hwei-Ming Chuang)} and 吳, {忠信(long-Shin Wu)} and 黃, {基礎(Ji-Chuu Hwang)}",

year = "1996",

doi = "10.29812/BBNTNU.199612.0006",

language = "繁體中文",

volume = "31",

pages = "141--148",

journal = "師大生物學報",

issn = "0378-8091",

publisher = "臺灣師範大學生命科學系",

number = "2",

}

TY - JOUR

T1 - 氨基啡林對大白鼠舌肌呼吸活動的影響

AU - 莊, 慧明(Hwei-Ming Chuang)

AU - 吳, 忠信(long-Shin Wu)

AU - 黃, 基礎(Ji-Chuu Hwang)

PY - 1996

Y1 - 1996

N2 - The purpose of the present study was to evaluate the response of genioglossus muscle (GG) to bolus injection of aminophvlline (AP). Adult rats were anesthetized with urethane. Electromyograms (EMG) of the GG and the diaphragm (Dia) were observed. Blood pressure was monitored. GG EMG increased to 144% (p＜.0.01) and Dia EMG enhanced to 111% in response to 4 mg/kg of AP. With high dose of AP treatment (32 mg/kg b.w.), GG EMG increased to 188% (p＜0.01) while Dia EMG argumented to 122% (p＜0.01). After peak response, Dia activity was gradually recovered to normal level. Yet, GG EMG was still higher than that of control 30 minutes alter high dose of AP treatment. These results indicate that Dia and GG activities were enhanced by AP and that enhancement of GG response is much more than that of the Dia.

AB - The purpose of the present study was to evaluate the response of genioglossus muscle (GG) to bolus injection of aminophvlline (AP). Adult rats were anesthetized with urethane. Electromyograms (EMG) of the GG and the diaphragm (Dia) were observed. Blood pressure was monitored. GG EMG increased to 144% (p＜.0.01) and Dia EMG enhanced to 111% in response to 4 mg/kg of AP. With high dose of AP treatment (32 mg/kg b.w.), GG EMG increased to 188% (p＜0.01) while Dia EMG argumented to 122% (p＜0.01). After peak response, Dia activity was gradually recovered to normal level. Yet, GG EMG was still higher than that of control 30 minutes alter high dose of AP treatment. These results indicate that Dia and GG activities were enhanced by AP and that enhancement of GG response is much more than that of the Dia.

KW - 氨基啡林

KW - 橫膈

KW - 舌肌

KW - 肌電圖

KW - 呼吸活動

KW - 大白鼠

KW - aminophylline

KW - diaphragm

KW - genioglossus muscle

KW - electromyogram

KW - respiratory activity

KW - rat

U2 - 10.29812/BBNTNU.199612.0006

DO - 10.29812/BBNTNU.199612.0006

M3 - 期刊論文

SN - 0378-8091

VL - 31

SP - 141

EP - 148

JO - 師大生物學報

JF - 師大生物學報

IS - 2

ER -