金屬催化串聯環化反應(3/3)

Since August, 2019 till now,. we have published 7 papers in the different international journals. We have developed microwave-assisted Ruthenium(II)-Catalyzed C?H/N?O activation of N-methoxybenzamides with alkynylsulfane for the synthesis of 4-thiosubstitutedisoquinolinone derivatives. Next, we synthesized 3-hydroxyisoindolinone derivatives through s a one one-pot tandem reaction of benzylcyanide 2-iodobenzamides in the presence of copper catalyst. Further we have eveloped an excellent methologies for the synthesis of pyrido[2,3-b]indoles via Bronsted acid promoted decarboxylative annulation of 3-bromopropenals and ethyl 2-amino-1H-indole-3-carboxylates. Furthermore, we have also developed several methodologies to access bioactive materials which are in midway.