金屬催化串聯環化反應(3/3)

Project: Government MinistryMinistry of Science and Technology

Project Details

Description

Since August, 2019 till now,. we have published 7 papers in the different international journals. We have developed microwave-assisted Ruthenium(II)-Catalyzed C?H/N?O activation of N-methoxybenzamides with alkynylsulfane for the synthesis of 4-thiosubstitutedisoquinolinone derivatives. Next, we synthesized 3-hydroxyisoindolinone derivatives through s a one one-pot tandem reaction of benzylcyanide 2-iodobenzamides in the presence of copper catalyst. Further we have eveloped an excellent methologies for the synthesis of pyrido[2,3-b]indoles via Bronsted acid promoted decarboxylative annulation of 3-bromopropenals and ethyl 2-amino-1H-indole-3-carboxylates. Furthermore, we have also developed several methodologies to access bioactive materials which are in midway.
StatusFinished
Effective start/end date2019/08/012020/07/31

Keywords

  • microwave-assisted
  • Ruthenium(II)-Catalyzed
  • copper catalyst
  • 4-thiosubstitutedisoquinolinone derivatives
  • 3-hydroxyisoindolinone derivatives

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