新型過渡金屬催化不對稱反應之研究發展及其應用於合成天然物與藥物分子

Project: Government MinistryMinistry of Science and Technology

Project Details

Description

This final report for the MOST financed project “” consists of fives distinct topics that are proposed to explore the catalytic activities and enantioselectivities of the chiral rhodium catalysts derived from a family of bicyclo[2.2.1]heptadiene ligands. Various known pharmaceutically active molecules and naturally occurring products were synthesized based on the designed and developed methods put forward in this research plan.
StatusFinished
Effective start/end date2018/08/012021/07/31

Keywords

  • transition-metal-catalyzed
  • asymmetric reaction
  • natural products synthesis
  • pharmaceutically active molecules
  • synthesis of beta-amino acids
  • synthesis of ipatasertib
  • synthesis of alpha-amino acids

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