國立臺灣師範大學貴重儀器使用中心服務計畫(總計畫)

The Instrumentation Center (IC), established in March of 2011, is supervised by the Office of Research and Development, NTNU. Currently, the 21 advanced instruments are managed by the IC. Among them, 7 state-of-the- art facilities are incorporated in the service project of Ministry of Science and Technology (MOST) and is listed below: 1. Nuclear Magnetic Resonance (NMR, Bruker AvanceIII HD-600 MHz, Bruker) In addition to regular parts, the TBO probe and autoloading system are set in the NMR. The TBO probe is specially made for a resonance of three various nuclides, i.e. 1H/19F/BB. In addition, two professors in Department of Chemistry are assigned to organize and evaluate the operation of this instrument. Moreover, in 2020, the majority of samples analyzed (80%) were from other universities or industrial companies. 2. High Resolution Mass Spectrometer (HRMS, JEOL JMS- 700,JEOL) The HRMS provides electron ionization (EI) or fast atom bombardment (FAB) to ionize samples. Most of all, the small molecular can be suitable for either ways. The excellent performance is provided and number of samples analyzed was 2941 in 2020. 3. Dual X-ray Single Crystal Diffractometer (SXRD, Bruker D8 Venture, Bruker) Thanks to its smart mechanism, not only the SXRD is an energy-saving style, but it also enhances work efficiency. The main analysis includes determinations of crystal system or lattice constant, data collections of X-ray single crystal diffraction, and analyses of crystal microstructure. In 2020, the majorities of samples analyzed were from NTNU. 4. Laser Scanning Confocal Microscope System (LSM, ZEISS LSM880 with airyscan, ZEISS) The LSM has been widely adopted to get single-point high resolution image, owing to its effective elimination of noise; it has been broadly used to observe the profiles of fluorescence-labeled samples upon varied time or cross section. The skills of live cell imaging and high-content imaging system have been applied in this system, as well. The number of samples analyzed was 416 in 2020. 5. High Resolution Electrospray Mass Spectrometry (HR-ESI MS, AB SCIEX QSTARR XL, AB SCIEX) Electrospray Ionization (ESI) is an important evolution for MS examinations, which extends MS detection to the biological field. ESI supplies the researches of biological samples with an efficient and accurate analysis. The number of samples analyzed was 1300 in 2020. 6. X-ray Powder Diffractometer (PXRD, Bruker D8 Advance, Bruker) The PXRD has been extensively used to obtain the XRD patents of inorganic materials, semiconductors, alloys, and so on. Furthermore, all crystalline parameters of detected samples could be evaluated via the XRD patents. The number of samples analyzed was 670 in 2020. 7. Electron Paramagnetic Resonance (EPR, Bruker EPR-plus, Bruker) The EPR, a spectroscopic technique, detects species in which unpaired electrons exist. Plenty of materials have unpaired electrons, including free radicals, many transition metal ions, and defects in materials. The studies of EPR crosses several subjects, including chemistry, physics, biology, materials science and medical science. The number of samples analyzed was 1230 in 2020.