Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Ying-Chieh Sun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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TrkB受體訊息傳遞路徑動力學及其雙穩態行為之計算研究
2022/08/01 → 2023/07/31
Project: Government Ministry › Ministry of Science and Technology
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新穎酵素蛋白質抑制劑的開發與設計:以分子動態模擬與酵素實驗研究蛋白質-配體結合自由能與結合構形
2017/08/01 → 2019/07/31
Project: Government Ministry › Ministry of Science and Technology
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Research output
- 46 Article
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Using ΔK280 TauRD Folding Reporter Cells to Screen TRKB Agonists as Alzheimer’s Disease Treatment Strategy
Weng, Z. K., Lin, T. H., Chang, K. H., Chiu, Y. J., Lin, C. H., Tseng, P. H., Sun, Y. C., Lin, W., Lee-Chen, G. J. & Chen, C. M., 2023 Feb, In: Biomolecules. 13, 2, 219.Research output: Contribution to journal › Article › peer-review
Open Access -
Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
Lin, C. H., Hsieh, Y. S., Sun, Y. C., Huang, W. H., Chen, S. L., Weng, Z. K., Lin, T. H., Wu, Y. R., Chang, K. H., Huang, H. J., Lee, G. C., Hsieh-Li, H. M. & Lee-Chen, G. J., 2023, In: Biomolecules and Therapeutics. 31, 1, p. 127-138 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Neuroprotective Action of Coumarin Derivatives through Activation of TRKB-CREB-BDNF Pathway and Reduction of Caspase Activity in Neuronal Cells Expressing Pro-Aggregated Tau Protein
Lin, T. H., Chang, K. H., Chiu, Y. J., Weng, Z. K., Sun, Y. C., Lin, W., Lee-Chen, G. J. & Chen, C. M., 2022 Nov, In: International journal of molecular sciences. 23, 21, 12734.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity
Chiu, Y. J., Lin, T. H., Chang, K. H., Lin, W., Hsieh-Li, H. M., Su, M. T., Chen, C. M., Sun, Y. C. & Lee-Chen, G. J., 2022, In: Aging. 14, 18, p. 7568-7586 19 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Flavones 7,8-DHF, Quercetin, and Apigenin Against Tau Toxicity via Activation of TRKB Signaling in ΔK280 TauRD-DsRed SH-SY5Y Cells
Chiang, N. N., Lin, T. H., Teng, Y. S., Sun, Y. C., Chang, K. H., Lin, C. Y., Hsieh-Li, H. M., Su, M. T., Chen, C. M. & Lee-Chen, G. J., 2021 Dec 15, In: Frontiers in Aging Neuroscience. 13, 758895.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus)
Datasets
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CCDC 228736: Experimental Crystal Structure Determination
Fan, C. L. (Creator), Lee, W. (Creator), Teng, N. (Creator), Sun, Y. (Creator) & Chen, K. (Creator), Unknown Publisher, 2004
DOI: 10.5517/cc7p0lh, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc7p0lh&sid=DataCite
Dataset
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CCDC 149602: Experimental Crystal Structure Determination
Leung, M. (Creator), Mandal, A. B. (Creator), Wang, C. (Creator), Lee, G. (Creator), Peng, S. (Creator), Cheng, H. (Creator), Her, G. (Creator), Chao, I. (Creator), Lu, H. (Creator), Sun, Y. (Creator), Shiao, M. (Creator) & Chou, P. (Creator), Unknown Publisher, 2002
DOI: 10.5517/cc50nwp, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc50nwp&sid=DataCite
Dataset
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CCDC 228734: Experimental Crystal Structure Determination
Fan, C. L. (Creator), Lee, W. (Creator), Teng, N. (Creator), Sun, Y. (Creator) & Chen, K. (Creator), Unknown Publisher, 2004
DOI: 10.5517/cc7p0jf, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc7p0jf&sid=DataCite
Dataset
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CCDC 228738: Experimental Crystal Structure Determination
Fan, C. L. (Creator), Lee, W. (Creator), Teng, N. (Creator), Sun, Y. (Creator) & Chen, K. (Creator), Unknown Publisher, 2004
DOI: 10.5517/cc7p0nk, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc7p0nk&sid=DataCite
Dataset
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CCDC 149603: Experimental Crystal Structure Determination
Leung, M. (Creator), Mandal, A. B. (Creator), Wang, C. (Creator), Lee, G. (Creator), Peng, S. (Creator), Cheng, H. (Creator), Her, G. (Creator), Chao, I. (Creator), Lu, H. (Creator), Sun, Y. (Creator), Shiao, M. (Creator) & Chou, P. (Creator), Unknown Publisher, 2002
DOI: 10.5517/cc50nxq, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc50nxq&sid=DataCite
Dataset