If you made any changes in Pure these will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Amyloid Medicine & Life Sciences
Islet Amyloid Polypeptide Medicine & Life Sciences
Oligomers Chemical Compounds
Medical problems Chemical Compounds
Type 2 Diabetes Mellitus Medicine & Life Sciences
Mass spectrometry Chemical Compounds
Poisons Medicine & Life Sciences
Agglomeration Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2004 2018

  • 614 Citations
  • 13 h-Index
  • 17 Article
  • 1 Commissioned report
  • 1 Review article

Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity

Tu, L. H., Tseng, N. H., Tsai, Y. R., Lin, T. W., Lo, Y. W., Charng, J. L., Hsu, H. T., Chen, Y. S., Chen, R. J., Wu, Y. T., Chan, Y. T., Chen, C. S., Fang, J. M. & Chen, Y. R., 2018 Oct 5, In : European Journal of Medicinal Chemistry. 158, p. 393-404 12 p.

Research output: Contribution to journalArticle

Caffeic Acids
Protein Multimerization
Dissociative Disorders
Peptide Fragments
Molecular Models
11 Citations (Scopus)

A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP

Serrano, A. L., Lomont, J. P., Tu, L-H., Raleigh, D. P. & Zanni, M. T., 2017 Nov 22, In : Journal of the American Chemical Society. 139, 46, p. 16748-16758 11 p.

Research output: Contribution to journalArticle

Energy barriers
Free energy
6 Citations (Scopus)

Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers

Young, L. M., Tu, L-H., Raleigh, D. P., Ashcroft, A. E. & Radford, S. E., 2017 Jan 1, In : Chemical Science. 8, 7, p. 5030-5040 11 p.

Research output: Contribution to journalArticle

Islet Amyloid Polypeptide
Electrospray ionization
42 Citations (Scopus)

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

Akter, R., Cao, P., Noor, H., Ridgway, Z., Tu, L. H., Wang, H., Wong, A. G., Zhang, X., Abedini, A., Schmidt, A. M. & Raleigh, D. P., 2016 Jan 1, In : Journal of Diabetes Research. 2016, 2798269.

Research output: Contribution to journalArticle

Islet Amyloid Polypeptide
Type 2 Diabetes Mellitus
Cell Death
Type 1 Diabetes Mellitus
33 Citations (Scopus)

Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics

Abedini, A., Plesner, A., Cao, P., Ridgway, Z., Zhang, J., Tu, L-H., Middleton, C. T., Chao, B., Sartori, D. J., Meng, F., Wang, H., Wong, A. G., Zanni, M. T., Verchere, C. B., Raleigh, D. P. & Schmidt, A. M., 2016 May 23, In : eLife. 5

Research output: Contribution to journalArticle

Time and motion study