Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 7 Finished
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以阿茲海默症模式小鼠分析潛力精神益生菌對腸道菌相與海馬迴基因網絡之影響
2022/08/01 → 2023/07/31
Project: Government Ministry › Ministry of Science and Technology
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以急性與慢性小鼠模式評估益生源乳果糖對阿茲海默症之預防與療效
2021/08/01 → 2022/07/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—阿茲海默氏症果蠅/小鼠模式平台(3/3)
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—阿茲海默氏症果蠅/小鼠模式平台(2/3)
2019/08/01 → 2020/07/31
Project: Government Ministry › Ministry of Science and Technology
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高壓氧治療SCA17小鼠之持久性、再現性、強度與分子效應
2019/08/01 → 2020/10/31
Project: Government Ministry › Ministry of Science and Technology
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Hyperbaric Oxygen Therapy Attenuated the Motor Coordination and Cognitive Impairment of Polyglutamine Spinocerebellar Ataxia SCA17 Mice
Chiang, M. K., Lin, T. C., Lin, K. H., Chang, Y. C., Hsieh-Li, H. M. & Lai, D. M., 2024 Apr, In: Cerebellum. 23, 2, p. 401-417 17 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
A Neuroprotective Action of Quercetin and Apigenin through Inhibiting Aggregation of Aβ and Activation of TRKB Signaling in a Cellular Experiment
Chiu, Y. J., Teng, Y. S., Chen, C. M., Sun, Y. C., Hsieh-Li, H. M., Chang, K. H. & Lee-Chen, G. J., 2023 May, In: Biomolecules and Therapeutics. 31, 3, p. 285-297 13 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
Lin, C. H., Hsieh, Y. S., Sun, Y. C., Huang, W. H., Chen, S. L., Weng, Z. K., Lin, T. H., Wu, Y. R., Chang, K. H., Huang, H. J., Lee, G. C., Hsieh-Li, H. M. & Lee-Chen, G. J., 2023, In: Biomolecules and Therapeutics. 31, 1, p. 127-138 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Correction: Lactobacillus plantarum PS128 prevents cognitive dysfunction in alzheimer’s disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis (BMC Complementary Medicine and Therapies, (2021), 21, 1, (259), 10.1186/s12906-021-03426-8)
Huang, H. J., Chen, J. L., Liao, J. F., Chen, Y. H., Chieu, M. W., Ke, Y. Y., Hsu, C. C., Tsai, Y. C. & Hsieh-Li, H. M., 2022 Dec, In: BMC Complementary Medicine and Therapies. 22, 1, 136.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Citation (Scopus) -
Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity
Chiu, Y. J., Lin, T. H., Chang, K. H., Lin, W., Hsieh-Li, H. M., Su, M. T., Chen, C. M., Sun, Y. C. & Lee-Chen, G. J., 2022, In: Aging. 14, 18, p. 7568-7586 19 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus)
Datasets
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Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer’s disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis
Huang, H. (Creator), Chen, J. (Creator), Liao, J. (Creator), Chen, Y. (Creator), Chieu, M. (Creator), Ke, Y. (Creator), Hsu, C. (Creator), Tsai, Y. (Creator) & Hsieh, H. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5655244.v1, https://springernature.figshare.com/collections/Lactobacillus_plantarum_PS128_prevents_cognitive_dysfunction_in_Alzheimer_s_disease_mice_by_modulating_propionic_acid_levels_glycogen_synthase_kinase_3_beta_activity_and_gliosis/5655244/1
Dataset
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Additional file 1 of Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer’s disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis
Huang, H. (Creator), Chen, J. (Creator), Liao, J. (Creator), Chen, Y. (Creator), Chieu, M. (Creator), Ke, Y. (Creator), Hsu, C. (Creator), Tsai, Y. (Creator) & Hsieh, H. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.16779829.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Lactobacillus_plantarum_PS128_prevents_cognitive_dysfunction_in_Alzheimer_s_disease_mice_by_modulating_propionic_acid_levels_glycogen_synthase_kinase_3_beta_activity_and_gliosis/16779829/1
Dataset
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Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer’s disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis
Huang, H. (Creator), Chen, J. (Creator), Liao, J. (Creator), Chen, Y. (Creator), Chieu, M. (Creator), Ke, Y. (Creator), Hsu, C. (Creator), Tsai, Y. (Creator) & Hsieh, H. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5655244, https://springernature.figshare.com/collections/Lactobacillus_plantarum_PS128_prevents_cognitive_dysfunction_in_Alzheimer_s_disease_mice_by_modulating_propionic_acid_levels_glycogen_synthase_kinase_3_beta_activity_and_gliosis/5655244
Dataset
Press/Media
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益生源乳果糖-對抗發炎與增加細胞自噬改善阿茲海默症
2021/10/13
1 item of Media coverage
Press/Media: research_highlight › Life Science