Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Guey-Jen Lee-Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 8 Finished
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效(II)(2/2)
Lee-Chen, G.-J. (PI)
2022/08/01 → 2023/07/31
Project: Government Ministry › Ministry of Science and Technology
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效(II)(1/2)
Lee-Chen, G.-J. (PI)
2021/08/01 → 2022/07/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—分子模擬、化學合成及高通量細胞篩選平台(3/3)
Lee-Chen, G.-J. (PI)
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效
Lee-Chen, G.-J. (PI)
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—分子模擬、化學合成及高通量細胞篩選平台(2/3)
Lee-Chen, G.-J. (PI)
2019/08/01 → 2020/07/31
Project: Government Ministry › Ministry of Science and Technology
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Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells
Chi, S. T., Wei, P. C., Chiu, Y. J., Lin, T. H., Lin, C. H., Chen, C. M., Yao, C. F., Lin, W., Lee-Chen, G. J. & Chang, K. H., 2025 Jan, In: Journal of Neurochemistry. 169, 1, e16300.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
The potential of mulberry (Morus alba L.) leaf extract against pro-aggregant tau-mediated inflammation and mitochondrial dysfunction
Lin, T. H., Tseng, P. H., Chen, I. C., Lin, C. Y., Lee, M. C., Chang, K. H., Lee-Chen, G. J. & Chen, C. M., 2025 Nov, In: Neurochemistry International. 190, 106042.Research output: Contribution to journal › Article › peer-review
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Coumarin-chalcone derivatives as dual NLRP1 and NLRP3 inflammasome inhibitors targeting oxidative stress and inflammation in neurotoxin-induced HMC3 and BE(2)-M17 cell models of Parkinson's disease
Lin, T. H., Chiu, Y. J., Lin, C. H., Chen, Y. R., Lin, W., Wu, Y. R., Chang, K. H., Chen, C. M. & Lee-Chen, G. J., 2024, In: Frontiers in Aging Neuroscience. 16, 1437138.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Investigating the therapeutic effects of novel compounds targeting inflammatory IL-1β and IL-6 signaling pathways in spinocerebellar ataxia type 3
Chen, I.-C., Chen, W. L., Chang, K. H., Lee, J. W., Lin, T. H., Lin, W., Chen, C. M. & Lee-Chen, G. J., 2024 Mar 15, In: European Journal of Pharmacology. 967, 176370.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Protective Effects of Coptis chinensis Rhizome Extract and Its Constituents (Berberine, Coptisine, and Palmatine) against α-Synuclein Neurotoxicity in Dopaminergic SH-SY5Y Cells
Lin, C. H., Wu, Y. R., Chao, C. Y., Chang, K. H., Chen, C. M., Chen, W. L., Yang, P. N. & Lee-Chen, G. J., 2024 Apr, In: Biological and Pharmaceutical Bulletin. 47, 4, p. 827-839 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus)
Press/Media
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以阿茲海默氏症細胞/小鼠模式探究查爾酮合成衍生物LM-031的多重標的效應
2020/10/13
1 item of Media coverage
Press/Media: research_highlight › Life Science