Projects per year
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效(II)(2/2)
2022/08/01 → 2023/07/31
Project: Government Ministry › Ministry of Science and Technology
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效(II)(1/2)
2021/08/01 → 2022/07/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—分子模擬、化學合成及高通量細胞篩選平台(3/3)
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—分子模擬、化學合成及高通量細胞篩選平台(2/3)
2019/08/01 → 2020/07/31
Project: Government Ministry › Ministry of Science and Technology
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Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
Lin, C. H., Hsieh, Y. S., Sun, Y. C., Huang, W. H., Chen, S. L., Weng, Z. K., Lin, T. H., Wu, Y. R., Chang, K. H., Huang, H. J., Lee, G. C., Hsieh-Li, H. M. & Lee-Chen, G. J., 2023, In: Biomolecules and Therapeutics. 31, 1, p. 127-138 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Isorhamnetin Attenuated the Release of Interleukin-6 from β -Amyloid-Activated Microglia and Mitigated Interleukin-6-Mediated Neurotoxicity
Wei, P. C., Lee-Chen, G. J., Chen, C. M., Chen, Y., Lo, Y. S. & Chang, K. H., 2022, In: Oxidative medicine and cellular longevity. 2022, 3652402.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Neuroprotective Action of Coumarin Derivatives through Activation of TRKB-CREB-BDNF Pathway and Reduction of Caspase Activity in Neuronal Cells Expressing Pro-Aggregated Tau Protein
Lin, T. H., Chang, K. H., Chiu, Y. J., Weng, Z. K., Sun, Y. C., Lin, W., Lee-Chen, G. J. & Chen, C. M., 2022 Nov, In: International journal of molecular sciences. 23, 21, 12734.Research output: Contribution to journal › Article › peer-review
Open Access -
Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity
Chiu, Y. J., Lin, T. H., Chang, K. H., Lin, W., Hsieh-Li, H. M., Su, M-T., Chen, C. M., Sun, Y-C. & Lee-Chen, G. J., 2022, In: Aging. 14, 18, p. 7568-7586 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of SOD2 p.V16A polymorphism with Parkinson's disease: A meta-analysis in Han Chinese
Wu, Y. R., Chang, K. H., Chao, C. Y., Lin, C. H., Chen, Y. C., Liu, T. W., Lee-Chen, G. J. & Chen, C. M., 2021 Jan, In: Journal of the Formosan Medical Association. 120, 1, p. 501-507 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)
Press / Media
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以阿茲海默氏症細胞/小鼠模式探究查爾酮合成衍生物LM-031的多重標的效應
2020/10/13
1 item of Media coverage
Press/Media: research_highlight › Life Science