Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Guey-Jen Lee-Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 8 Finished
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效(II)(2/2)
2022/08/01 → 2023/07/31
Project: Government Ministry › Ministry of Science and Technology
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效(II)(1/2)
2021/08/01 → 2022/07/31
Project: Government Ministry › Ministry of Science and Technology
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探究新穎香豆素-查耳酮雜合物LM-021和吲哚衍生物NC009-1的抗發炎和抗氧化作用對巴金森氏症細胞和小鼠模型的療效
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—分子模擬、化學合成及高通量細胞篩選平台(3/3)
2020/08/01 → 2021/10/31
Project: Government Ministry › Ministry of Science and Technology
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以BDNF受體TRKB為標的開發治療退化性神經疾病之小分子促效劑藥物—分子模擬、化學合成及高通量細胞篩選平台(2/3)
2019/08/01 → 2020/07/31
Project: Government Ministry › Ministry of Science and Technology
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A Neuroprotective Action of Quercetin and Apigenin through Inhibiting Aggregation of Aβ and Activation of TRKB Signaling in a Cellular Experiment
Chiu, Y. J., Teng, Y. S., Chen, C. M., Sun, Y. C., Hsieh-Li, H. M., Chang, K. H. & Lee-Chen, G. J., 2023 May, In: Biomolecules and Therapeutics. 31, 3, p. 285-297 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Coumarin-chalcone hybrid LM-021 and indole derivative NC009-1 targeting inflammation and oxidative stress to protect BE(2)-M17 cells against α-synuclein toxicity
Yang, P. N., Chen, W. L., Lee, J. W., Lin, C. H., Chen, Y. R., Lin, C. Y., Lin, W., Yao, C. F., Wu, Y. R., Chang, K. H., Chen, C. M. & Lee-Chen, G. J., 2023, In: Aging. 15, 16, p. 8061-8089 29 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort
the MJFF Global Genetic Parkinson's Disease Study Group, 2023 Feb 1, In: Movement Disorders. 38, 2, p. 286-303 18 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin-Induced Cell and Mouse Models of Parkinson’s Disease
Chiu, Y. J., Lin, C. H., Lin, C. Y., Yang, P. N., Lo, Y. S., Chen, Y. C., Chen, C. M., Wu, Y. R., Yao, C. F., Chang, K. H. & Lee-Chen, G. J., 2023 Feb, In: International journal of molecular sciences. 24, 3, 2642.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Using ΔK280 TauRD Folding Reporter Cells to Screen TRKB Agonists as Alzheimer’s Disease Treatment Strategy
Weng, Z. K., Lin, T. H., Chang, K. H., Chiu, Y. J., Lin, C. H., Tseng, P. H., Sun, Y. C., Lin, W., Lee-Chen, G. J. & Chen, C. M., 2023 Feb, In: Biomolecules. 13, 2, 219.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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以阿茲海默氏症細胞/小鼠模式探究查爾酮合成衍生物LM-031的多重標的效應
2020/10/13
1 item of Media coverage
Press/Media: research_highlight › Life Science