Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Guan-Chiun Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Enzymatic Production of Trehalose and Trehalulose by Immobilized Thermostable Trehalose Synthase
Yong, Z. L., Chen, Y. T., Chan, C. & Lee, G.-C., 2024, (Accepted/In press) In: Journal of Agricultural and Food Chemistry.Research output: Contribution to journal › Article › peer-review
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Paeonol Derivative, 6′-Methyl Paeonol, Attenuates Aβ-Induced Pathophysiology in Cortical Neurons and in an Alzheimer’s Disease Mice Model
Chen, P. J., Yao, C. A., Chien, P. C., Tsai, H. J., Chen, Y. R., Chuang, J. H., Chou, P. L., Lee, G. C., Lin, W. & Lin, Y., 2024 Feb 21, In: ACS Chemical Neuroscience. 15, 4, p. 724-734 11 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Early Life Exposure to C16-Ceramide Improves Learning and Short-Term Memory Behavior during Adulthood in Mice
Yeh, C. M., Sun, Y. Y., Chen, T. Y., Hung, Y., Lee, G. C., Yang, W. C. & Lin, Y., 2023, (Accepted/In press) In: ACS Chemical Neuroscience.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
Lin, C. H., Hsieh, Y. S., Sun, Y. C., Huang, W. H., Chen, S. L., Weng, Z. K., Lin, T. H., Wu, Y. R., Chang, K. H., Huang, H. J., Lee, G. C., Hsieh-Li, H. M. & Lee-Chen, G. J., 2023, In: Biomolecules and Therapeutics. 31, 1, p. 127-138 12 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
Prebiotic Lactulose Ameliorates the Cognitive Deficit in Alzheimer's Disease Mouse Model through Macroautophagy and Chaperone-Mediated Autophagy Pathways
Lee, Y. S., Lai, D. M., Huang, H. J., Lee-Chen, G. J., Chang, C. H., Hsieh-Li, H. M. & Lee, G. C., 2021 Mar 3, In: Journal of Agricultural and Food Chemistry. 69, 8, p. 2422-2437 16 p.Research output: Contribution to journal › Article › peer-review
69 Citations (Scopus)
Datasets
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The N253F mutant structure of trehalose synthase from Deinococcus radiodurans reveals an open active-site conformation
Chow, S.-Y. (Contributor), Wang, Y.-L. (Contributor), Hsieh, Y.-C. (Contributor), Lee, G.-C. (Contributor) & Liaw, S.-H. (Contributor), Protein Data Bank (PDB), 2017 Oct 25
DOI: 10.2210/pdb5YKB/pdb, https://www.wwpdb.org/pdb?id=pdb_00005ykb
Dataset
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Crystal structure of trehalose synthase from Deinococcus radiodurans reveals a closed conformation for catalysis of the intramolecular isomerization
Wang, Y.-L. (Contributor), Chow, S.-Y. (Contributor), Lin, Y.-T. (Contributor), Hsieh, Y.-C. (Contributor), Lee, G.-C. (Contributor), Liaw, S.-H. (Contributor), Wang, J.-H. (Contributor), Tsai, M.-Y. (Contributor), Chen, J.-J. (Contributor) & Shaw, J.-F. (Contributor), Protein Data Bank (PDB), 2014 Dec 17
DOI: 10.2210/pdb4TVU/pdb, https://www.wwpdb.org/pdb?id=pdb_00004tvu
Dataset
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A. Fulgidus lipase with fatty acid fragment and magnesium
Chen, C.K.-M. (Contributor), Lee, G.-C. (Contributor), Ko, T.-P. (Contributor), Guo, R.-T. (Contributor), Huang, L.-M. (Contributor), Liu, H.-J. (Contributor), Ho, Y.-F. (Contributor), Shaw, J.-F. (Contributor) & Wang, A.H.-J. (Contributor), Protein Data Bank (PDB), 2009 Jun 16
DOI: 10.2210/pdb2ZYR/pdb, https://www.wwpdb.org/pdb?id=pdb_00002zyr
Dataset
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mutant A. Fulgidus lipase S136A complexed with fatty acid fragment
Chen, C.K.-M. (Contributor), Lee, G.-C. (Contributor), Ko, T.-P. (Contributor), Guo, R.-T. (Contributor), Huang, L.-M. (Contributor), Liu, H.-J. (Contributor), Ho, Y.-F. (Contributor), Shaw, J.-F. (Contributor) & Wang, A.H.-J. (Contributor), Protein Data Bank (PDB), 2009 Jun 16
DOI: 10.2210/pdb2ZYH/pdb, https://www.wwpdb.org/pdb?id=pdb_00002zyh
Dataset
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A. Fulgidus lipase with fatty acid fragment and chloride
Chen, C.K.-M. (Contributor), Lee, G.-C. (Contributor), Ko, T.-P. (Contributor), Guo, R.-T. (Contributor), Huang, L.-M. (Contributor), Liu, H.-J. (Contributor), Ho, Y.-F. (Contributor), Shaw, J.-F. (Contributor) & Wang, A.H.-J. (Contributor), Protein Data Bank (PDB), 2009 Jun 16
DOI: 10.2210/pdb2ZYS/pdb, https://www.wwpdb.org/pdb?id=pdb_00002zys
Dataset