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Fingerprint Dive into the research topics where Guan-Chiun Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Lipase Medicine & Life Sciences
Candida Medicine & Life Sciences
Candida rugosa Agriculture & Biology
Pichia Medicine & Life Sciences
Genes Chemical Compounds
Codon Medicine & Life Sciences
Trehalose Medicine & Life Sciences
Mutagenesis Chemical Compounds

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Research Output 1999 2019

  • 1481 Citations
  • 20 h-Index
  • 44 Article
  • 3 Review article
1 Citation (Scopus)

Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice

Huang, H. J., Chen, S. L., Huang, H. Y., Sun, Y. C., Lee, G. C., Lee-Chen, G. J., Hsieh-Li, H. M. & Su, M. T., 2019 Feb 14, In : Psychopharmacology. 236, 2, p. 763-773 11 p.

Research output: Contribution to journalArticle

Open Access
Alzheimer Disease
Hyperglycemia
N-(4-hydroxyphenyl)arachidonylamide
Cognitive Dysfunction
Inflammation
1 Citation (Scopus)
Alzheimer Disease
Inflammation
Green Fluorescent Proteins
p38 Mitogen-Activated Protein Kinases
Acetylcholinesterase

Genetic and functional characters of GRN p.T487I mutation in Taiwanese patients with atypical parkinsonian disorders

Chang, K. H., Lee, G-C., Huang, C. C., Kuo, H. C., Chen, C. M., Hsiao, Y. C., Hsu, H. C., Hsu, K. J., Lin, C. H., Chang, C. W., Lee, G-J. & Wu, Y. R., 2018 Jun 1, In : Parkinsonism and Related Disorders. 51, p. 61-66 6 p.

Research output: Contribution to journalArticle

Parkinsonian Disorders
Mutation
Frontotemporal Dementia
Protein Stability
Kidney
2 Citations (Scopus)

Investigation of the bindings of a class of inhibitors with GSK3β kinase using thermodynamic integration MD simulation and kinase assay

Hsu, C. J., Hsu, W. C., Lee, D. J., Liu, A. L., Chang, C. M., Shih, H. J., Huang, W. H., Lee, G-J., Hsieh, H. M., Lee, G-C. & Sun, Y-C., 2017 Aug 1, In : Chemical Biology and Drug Design. 90, 2, p. 272-281 10 p.

Research output: Contribution to journalArticle

Molecular Dynamics Simulation
Thermodynamics
Molecular dynamics
Assays
Phosphotransferases

The N253F mutant structure of trehalose synthase from Deinococcus radiodurans reveals an open active-site topology

Chow, S. Y., Wang, Y. L., Hsieh, Y. C., Lee, G-C. & Liaw, S. H., 2017 Nov 1, In : Acta Crystallographica Section F:Structural Biology Communications. 73, 11, p. 588-594 7 p.

Research output: Contribution to journalArticle

Deinococcus
Catalytic Domain
topology
Glycoside Hydrolases
Topology