• 4333 Citations
  • 36 h-Index
1988 …2020

Research output per year

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Research Output

2020

Diabetes upregulates oxidative stress and downregulates cardiac protection to exacerbate myocardial ischemia/reperfusion injury in rats

Chien, C. Y., Wen, T. J., Cheng, Y. H., Tsai, Y. T., Chiang, C. Y. & Chien, C. T., 2020 Aug, In : Antioxidants. 9, 8, p. 1-18 18 p., 679.

Research output: Contribution to journalArticle

Open Access
Open Access
3 Citations (Scopus)
1 Citation (Scopus)

Sulforaphane improves voiding function via the preserving mitochondrial function in diabetic rats

Lin, C. F., Chueh, T. H., Chung, C. H., Chung, S. D., Chang, T. C. & Chien, C. T., 2020 Sep, In : Journal of the Formosan Medical Association. 119, 9, p. 1422-1430 9 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Thromboxane A2 Synthase and Thromboxane Receptor Deletion Reduces Ischaemia/Reperfusion-Evoked Inflammation, Apoptosis, Autophagy and Pyroptosis

Chueh, T. H., Cheng, Y. H., Chen, K. H. & Chien, C. T., 2020, In : Thrombosis and Haemostasis. 120, 2, p. 329-343 15 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Aromatherapy: Activating olfactory calcium-sensing receptors impairs renal hemodynamics via sympathetic nerve-mediated vasoconstriction

Lee, S. P., Wu, W. Y., Hsiao, J. K., Zhou, J. H., Chang, H. H. & Chien, C. T., 2019 Jan 1, In : Acta Physiologica. 225, 1, e13157.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cisplatin exposure impairs ionocytes and hair cells in the skin of zebrafish embryos

Hung, G. Y., Wu, C. L., Chou, Y. L., Chien, C. T., Horng, J. L. & Lin, L. Y., 2019 Apr 1, In : Aquatic Toxicology. 209, p. 168-177 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Glycine tomentella hayata extract and its ingredient daidzin ameliorate cyclophosphamide-induced hemorrhagic cystitis and oxidative stress through the action of antioxidation, anti-fibrosis, and anti-inflammation

Wu, K. C., Lin, W. Y., Sung, Y. T., Wu, W. Y., Cheng, Y. H., Chen, T. S., Chiang, B. J. & Chien, C. T., 2019 Sep 1, In : Chinese Journal of Physiology. 62, 5, p. 188-195 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018
Open Access
5 Citations (Scopus)

Genetic Depletion of Thromboxane A 2 /Thromboxane-Prostanoid Receptor Signalling Prevents Microvascular Dysfunction in Ischaemia/Reperfusion Injury

Chiang, C. Y., Chien, C. Y., Qiou, W. Y., Chang, C., Yu, I. S., Chang, P. Y. & Chien, C. T., 2018 Jan 1, In : Thrombosis and Haemostasis. 118, 11, p. 1982-1996 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

I-Tiao-Gung extract through its active component daidzin improves cyclophosphamide-induced bladder dysfunction in rat model

Wu, K. C., Chiang, B. J., Tsai, W. H., Chung, S. D. & Chien, C. T., 2018 Nov 1, In : Neurourology and Urodynamics. 37, 8, p. 2560-2570 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Association of mSin1 with mTORC2 Ras and Akt reveals a crucial domain on mSin1 involved in Akt phosphorylation

Yao, C. A., Ortiz-Vega, S., Sun, Y. Y., Chien, C. T., Chuang, J. H. & Lin, Y., 2017, In : Oncotarget. 8, 38, p. 63392-63404 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
19 Citations (Scopus)
12 Citations (Scopus)

Synthetic nickel-containing superoxide dismutase attenuates para-phenylenediamine-induced bladder dysfunction in rats

Chiang, B. J., Chen, T. W., Chung, S. D., Lee, W. Z. & Chien, C. T., 2017 Nov 11, In : Oncotarget. 8, 62, p. 105735-105748 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016
7 Citations (Scopus)
Open Access
14 Citations (Scopus)

Monascus Adlay and Monacolin K Attenuates Arterial Thrombosis in Rats through the Inhibition of ICAM-1 and Oxidative Stress

Tien, A. J., Chueh, T. H., Hsia, C. P. & Chien, C. T., 2016 Dec 1, In : Kidney and Blood Pressure Research. 41, 6, p. 815-827 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Predicting stroke volume and arterial pressure fluid responsiveness in liver cirrhosis patients using dynamic preload variables

Wu, C. Y., Cheng, Y. J., Liu, Y. J., Wu, T. T., Chien, C. T. & Chan, K. C., 2016 Sep 1, In : European Journal of Anaesthesiology. 33, 9, p. 645-652 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
Open Access
10 Citations (Scopus)
25 Citations (Scopus)

Soy-based multiple amino acid oral supplementation increases the anti-sarcoma effect of cyclophosphamide

Yao, C. A., Chen, C. C., Wang, N. P. & Chien, C. T., 2016 Apr 1, In : Nutrients. 8, 4, 192.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Statins Improve Long Term Patency of Arteriovenous Fistula for Hemodialysis

Chang, H. H., Chang, Y. K., Lu, C. W., Huang, C. T., Chien, C. T., Hung, K. Y., Huang, K. C. & Hsu, C. C., 2016 Feb 23, In : Scientific Reports. 6, 22197.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)
5 Citations (Scopus)
2015

Design of complementary tilt-gate TFETs with SiGe/Si and III-V integrations feasible for ultra-low-power applications

Hsieh, E. R., Lin, Y. S., Zhao, Y. B., Liu, C. H., Chien, C. H. & Chung, S. S., 2015 Sep 24, 2015 Silicon Nanoelectronics Workshop, SNW 2015. Institute of Electrical and Electronics Engineers Inc., 7275322. (2015 Silicon Nanoelectronics Workshop, SNW 2015).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Effect of adenoviral catalase gene transfer on renal ischemia/reperfusion injury in rats

Yang, C. C., Hsu, S. P., Chen, K. H. & Chien, C. T., 2015 Jan 1, In : Chinese Journal of Physiology. 58, 6, p. 420-430 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Effects of different types of fluid resuscitation for hemorrhagic shock on splanchnic organ microcirculation and renal reactive oxygen species formation

The NTUH Center of Microcirculation Medical Research (NCMMR), 2015 Dec 11, In : Critical Care. 19, 1, 434.

Research output: Contribution to journalArticle

29 Citations (Scopus)
20 Citations (Scopus)

Laser speckle contrast imaging for assessing microcirculatory changes in multiple splanchnic organs and the gracilis muscle during hemorrhagic shock and fluid resuscitation

on behalf of the NTUH Center of Microcirculation Medical Research (NCMMR), 2015 Sep 1, In : Microvascular Research. 101, p. 55-61 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Oral treatment with herbal formula B401 alleviates penile toxicity in aging mice with manganism

Hsu, C. H., Lin, C. L., Wang, S. E., Sheu, S. J., Chien, C. T. & Wu, C. H., 2015 May 28, In : Clinical Interventions in Aging. 10, p. 907-918 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis

Lien, C. Y., Chuang, T. Y., Hsu, C. H., Lin, C. L., Wang, S. E., Sheu, S. J., Chien, C. T. & Wu, C. H., 2015, In : OncoTargets and Therapy. 8, p. 1193-1210 18 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Treatment with a herbal formula B401 enhances neuroprotection and angiogenesis in the R6/2 mouse model of Huntington’s disease

Wang, S. E., Lin, C. L., Hsu, C. H., Sheu, S. J., Chien, C. T. & Wu, C. H., 2015 Feb 16, In : Drug Design, Development and Therapy. 9, p. 887-900 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Deep-sea water containing selenium provides intestinal protection against duodenal ulcers through the upregulation of Bcl-2 and thioredoxin reductase 1

Yang, C. C., Yao, C. A., Lin, Y. R., Yang, J. C. & Chien, C. T., 2014 Jul 1, In : PloS one. 9, 7, e96006.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prediction of severe neonatal hyperbilirubinemia using cord blood hydrogen peroxide: A prospective study

Chou, H. C., Chien, C. T., Tsao, P. N., Hsieh, W. S., Chen, C. Y. & Chang, M. H., 2014 Jan 23, In : PloS one. 9, 1, e86797.

Research output: Contribution to journalArticle

4 Citations (Scopus)
16 Citations (Scopus)

Proteomic analysis of osteoarthritic chondrocyte reveals the hyaluronic acid-regulated proteins involved in chondroprotective effect under oxidative stress

Yu, C. J., Ko, C. J., Hsieh, C. H., Chien, C. T., Huang, L. H., Lee, C. W. & Jiang, C. C., 2014 Mar 17, In : Journal of Proteomics. 99, p. 40-53 14 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
36 Citations (Scopus)
2013

Alterations in peripheral purinergic and muscarinic signaling of rat bladder after long-term fructose-induced metabolic syndrome

Chung, S. D., Chien, C. T. & Yu, H. J., 2013 Feb 1, In : European Journal of Nutrition. 52, 1, p. 347-359 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Augmented renal prostacyclin by intrarenal bicistronic cyclo-oxygenase-1/ Prostacyclin synthase gene transfer attenuates renal ischemia-reperfusion injury

Yang, C. C., Chen, K. H., Hsu, S. P. & Chien, C. T., 2013 Dec 27, In : Transplantation. 96, 12, p. 1043-1051 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Catechins and sialic acid attenuate helicobacter pylori -triggered epithelial caspase-1 activity and eradicate helicobacter pylori infection

Yang, J. C., Yang, H. C., Shun, C. T., Wang, T. H., Chien, C. T. & Kao, J. Y., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 248585.

Research output: Contribution to journalArticle

21 Citations (Scopus)
7 Citations (Scopus)

Electrospun scaffolds composing of alginate, chitosan, collagen and hydroxyapatite for applying in bone tissue engineering

Yu, C. C., Chang, J. J., Lee, Y. H., Lin, Y. C., Wu, M. H., Yang, M. C. & Chien, C. T., 2013 Jan 7, In : Materials Letters. 93, p. 133-136 4 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Glucagon-like peptide-1 receptor agonist activation ameliorates venous thrombosis- induced arteriovenous fistula failure in chronic kidney d isease

Chien, C. T., Fan, S. C., Lin, S. C., Kuo, C. C., Yang, C. H., Yu, T. Y., Lee, S. P., Cheng, D. Y. & Li, P. C., 2013 Nov 1, In : Thrombosis and Haemostasis. 112, 5, p. 1051-1064 14 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Therapeutic potential of traditional chinese medicine on inflammatory diseases

Tsai, W. H., Yang, C. C., Li, P. C., Chen, W. C. & Chien, C. T., 2013 Jan 1, In : Journal of Traditional and Complementary Medicine. 3, 3, p. 142-151 10 p.

Research output: Contribution to journalReview article

21 Citations (Scopus)
2012

Acceleration of wound healing in diabetic rats by layered hydrogel dressing

Lee, Y. H., Chang, J. J., Yang, M. C., Chien, C. T. & Lai, W. F., 2012 Apr 15, In : Carbohydrate Polymers. 88, 3, p. 809-819 11 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Activating Nrf-2 Signaling Depresses Unilateral Ureteral Obstruction-Evoked Mitochondrial Stress-Related Autophagy, Apoptosis and Pyroptosis in Kidney

Chung, S. D., Lai, T. Y., Chien, C. T. & Yu, H. J., 2012 Oct 10, In : PloS one. 7, 10, e47299.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Antioxidant sol-gel improves cutaneous wound healing in streptozotocin-induced diabetic rats

Lee, Y. H., Chang, J. J., Chien, C. T., Yang, M. C. & Chien, H. F., 2012, In : Experimental Diabetes Research. 2012, 504693.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Electrospun anti-adhesion barrier made of chitosan alginate for reducing peritoneal adhesions

Chang, J. J., Lee, Y. H., Wu, M. H., Yang, M. C. & Chien, C. T., 2012 May 16, In : Carbohydrate Polymers. 88, 4, p. 1304-1312 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Green tea extract supplementation ameliorates CCl4-induced hepatic oxidative stress, fibrosis, and acute-phase protein expression in rat

Hung, G. D., Li, P. C., Lee, H. S., Chang, H. M., Chien, C. T. & Lee, K. L., 2012 Oct 1, In : Journal of the Formosan Medical Association. 111, 10, p. 550-559 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)