The Permian silicic rocks in the Phan Si Pan (PSP) uplift area and Tu Le (TL) basin of NW Vietnam (collectively the PSP–TL region) are associated with the Emeishan Large Igneous Province (ELIP). The Permian Muong Hum, Phu Sa Phin, and Nam Xe–Tam Duong granites, and Tu Le rhyolites are alkali ferroan A1-type granitic rocks, which likely formed by fractional crystallization of high-Ti basaltic magma that was contaminated by melts derived from the Neoproterozoic host rocks. Zircon U–Pb LA-ICP-MS geochronology yielded weighted-mean 206Pb/238U ages of 246 ± 3 Ma to 259 ± 3 Ma for granites, and 249 ± 3 Ma and 254 ± 2 Ma for rhyolites. This is contrasted with previously-published high precision U–Pb ages, obtained using CA-ID-TIMS method applied on the same zircon grains, which suggest that the calculated LA-ICP-MS U–Pb ages are variably inaccurate by up to 10 Ma, though at the single-grain level dates generally agree within uncertainty. The similarity of rock texture, whole-rock geochemistry, emplacement ages, and fractionation phases between the PSP–TL region and silicic rocks in the Inner Zone ELIP (i.e. Panzhihua, Binchuan) suggests they were spatially proximal before being sinistrally displaced along the Ailao Shan–Red River shear zone.